Evidence map›Paper›PMID 40178111›Full record

ArticleResearch in psychotherapy (Milano)2025

Defense mechanisms and inflammatory bowel diseases: a narrative review.

Orlando Silvestro, Carmelo M Vicario, Ludovico Costa, Giorgio Sparacino, Trine Lund-Jacobsen, Chiara A M Spatola, Emanuele M Merlo, Anna Viola, Concetto M Giorgianni, Antonino Catalano and 3 more

Abstract read
In one paragraph

Article in Research in psychotherapy (Milano), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Orlando SilvestroDepartment of Health Sciences, University Magna Graecia of Catanzaro.ORCID 0009-0002-0966-5642
Carmelo M VicarioDepartment of Cognitive Science, Psychology, Education and Cultural Studies, University of Messina.
Ludovico CostaCourse Degree in Clinical and Health Psychology in the Life Cycle, University of Messina.ORCID 0009-0007-4443-319X
Giorgio SparacinoCourse Degree in Medicine and Surgery, University of Messina.
Trine Lund-JacobsenDepartment of Endocrinology, Centre for Cancer and Organ Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen.ORCID 0000-0002-3616-5929
Chiara A M SpatolaDepartment of Clinical and Experimental Medicine, University of Messina.ORCID 0000-0003-4807-9566
Emanuele M MerloDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina.ORCID 0000-0001-6041-9186
Anna ViolaDepartment of Clinical and Experimental Medicine, University of Messina.
Concetto M GiorgianniDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina.
Antonino CatalanoDepartment of Clinical and Experimental Medicine, University of Messina.
Walter FriesDepartment of Clinical and Experimental Medicine, University of Messina.ORCID 0000-0001-6159-7478
Gianluca Lo CocoDepartment of Psychology, Educational Science and Human Movement, University of Palermo.
Gabriella MartinoDepartment of Clinical and Experimental Medicine, University of Messina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing evidence highlights the crucial role of defense mechanisms in the context of chronic diseases. However, few studies have evaluated the impact of these implicit emotion regulation strategies on the adaptation processes related to inflammatory bowel diseases (IBD). This narrative review aimed to explore the role of defense mechanisms in patients with IBD and clarify their association with related psychological and physical symptoms. A literature search was conducted using PubMed and PsycINFO databases to select studies considering defense mechanisms in patients with IBD. Inclusion criteria were English language articles, diagnosis of Crohn's disease or ulcerative colitis, and use of validated assessment instruments specifically related to defense mechanisms. Six studies, including a total of 664 patients, were deemed eligible. Immature defense mechanisms were commonly detected in IBD patients, with significant effects on psychological and physical health. Significant associations were found between defense mechanisms, perceived health-related quality of life (HR-QoL), and psychological distress. Findings suggested that immature defense mechanisms may negatively impact the management of disease, leading to lower perceived HR-QoL, decreased treatment adherence, and increased risk of psychopathological symptoms. Considering these findings, we suggest that an integrated clinical evaluation, including an in-depth investigation of defense mechanisms, may promote more effective psychological treatments and improve psychological well-being in patients suffering from IBD.

Identifiers

PMID40178111
PMCPMC12203894

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.