Evidence mapPaperPMID 40178150Full record

ReviewThe Plant cell2025

Challenges of translating Arabidopsis insights into crops.

Cristóbal Uauy, Hilde Nelissen, Raquel Lía Chan, Johnathan A Napier, David Seung, Linsan Liu, Sarah M McKim

Abstract readReview
In one paragraph

Review in The Plant cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Root Meristem Maintenance Mechanisms are Key to Plant Defense Against Nanoplastics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristóbal UauyJohn Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.ORCID 0000-0002-9814-1770
Hilde NelissenDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent B-9052, Belgium.ORCID 0000-0001-7494-1290
Raquel Lía ChanInstituto de Agrobiotecnología del Litoral, Universidad Nacional del Litoral-CONICET, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.ORCID 0000-0002-3264-0008
Johnathan A NapierRothamsted Research, Harpenden, Herts AL5 2JQ, UK.ORCID 0000-0003-3580-3607
David SeungJohn Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.ORCID 0000-0003-3905-3647
Linsan LiuDivision of Plant Sciences, School of Life Sciences, University of Dundee, Dundee DD2 5DA, UK.ORCID 0000-0002-1084-0201
Sarah M McKimDivision of Plant Sciences, School of Life Sciences, University of Dundee, Dundee DD2 5DA, UK.ORCID 0000-0002-8893-9498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The significance of research conducted on Arabidopsis thaliana cannot be overstated. This focus issue showcases how insights from Arabidopsis have opened new areas of biology and directly advanced our understanding of crops. Here, experts intimately involved in bridging between Arabidopsis and crops share their perspectives on the challenges and opportunities for translation. First, we examine the translatability of genetic modules from Arabidopsis into maize, emphasizing the need to publish well-executed translational experiments, regardless of outcome. Second, we highlight the landmark success of HB4, the first GM wheat cultivar on the market, whose abiotic tolerance is borne from direct translation and based on strategies first outlined in Arabidopsis. Third, we discuss the decades-long journey to engineer oilseed crops capable of producing omega-3 fish oils, with Arabidopsis serving as a critical intermediary. Fourth, we explore how direct translation of starch synthesizing proteins characterized in Arabidopsis helped uncover novel mechanisms and functions in crops, with potential valuable applications. Finally, we illustrate how shared molecular factors between Arabidopsis and barley exhibit distinct molecular wiring as exemplified in cuticular and stomatal development. Together, these vignettes underscore the pivotal role of Arabidopsis as a foundational model plant while highlighting the challenges of translating discoveries into field-ready, commercial cultivars with enhanced knowledge-based traits.

Indexed as

ArabidopsisCrops, AgriculturalPlants, Genetically ModifiedTriticumZea mays

Identifiers

PMID40178150
PMCPMC12079398

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.