ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025
Consistent Hierarchies of Single-Neuron Timescales in Mice, Macaques, and Humans.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Neural timescales from a computational perspective.Nature neuroscience · 2026Review
- Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey.Scientific data · 2026Article
- Selective control of prefrontal neural timescales by parietal cortex.Nature communications · 2026Article
- iSTTC: A robust method for accurate estimation of intrinsic neural timescales from single-unit recordings.PLoS computational biology · 2026Article
- A prefrontal cortex map based on single-neuron activity.Nature neuroscience · 2026Article
- A Closed-Loop-Capable Neural Interface Platform for Deep Brain Modulation via Integrated Non-Viral Gene Delivery, NIR Optogenetics, and Electrophysiological Recording.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Facilitating analysis of open neurophysiology data on the DANDI Archive using large language model tools.Scientific data · 2025Article
- Brain-wide organization of intrinsic timescales at single-neuron resolution.bioRxiv : the preprint server for biology · 2025Article
- Facilitating analysis of open neurophysiology data on the DANDI Archive using large language model tools.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Update of
Authors and funding
5 authors.
Funding
Abstract
The intrinsic timescales of single neurons are thought to be hierarchically organized across the cortex, but whether hierarchical variation in timescales is a general brain organizing principle across mammalian species remains unclear. Here, we took a cross-species approach and estimated neuronal timescales of thousands of single neurons recorded across frontal cortex, amygdala, and hippocampus in mice, monkeys, and humans of both sexes using a task-agnostic method. We identify largely consistent hierarchies of timescales in frontal and limbic regions across species: hippocampus had the shortest timescale whereas anterior cingulate cortex had the longest. Within this scheme, variability across species was found, most notably in amygdala and orbitofrontal cortex. We show that variation in timescales is not simply related to differences in spiking statistics nor the result of cytoarchitectonic features such as cortical granularity. Thus, hierarchically organized timescales are a consistent organizing principle across species and appear to be related to a combination of intrinsic and extrinsic factors.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.