Evidence map›Paper›PMID 40181835›Full record

ArticleOpen medicine (Warsaw, Poland)2025

Clinical efficacy of azacitidine in the treatment of middle- and high-risk myelodysplastic syndrome in middle-aged and elderly patients: A retrospective study.

Liang Li, Jianjun Bian, Yuxuan Su, Chunchun Zhang

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liang LiDepartment of Hematology, The Second Affiliated Hospital of Bengbu Medical University, No. 633 Longhua Road, Huaishang District, Bengbu City, 233000, China.
Jianjun BianDepartment of Hematology, The Second Affiliated Hospital of Bengbu Medical University, Bengbu City, 233000, China.
Yuxuan SuDepartment of Hematology, The Second Affiliated Hospital of Bengbu Medical University, Bengbu City, 233000, China.
Chunchun ZhangDepartment of Hematology, The Second Affiliated Hospital of Bengbu Medical University, Bengbu City, 233000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to explore the efficacy and safety of azacitidine (AZA) in middle-aged and elderly patients with myelodysplastic syndrome (MDS). Methods: The clinical data of 59 middle-aged and elderly patients with middle- and high-risk MDS, who attended our hospital from April 2019 to January 2024, were retrospectively analyzed and were divided into an observation group (AZA) and a control group (conventional supportive treatment) according to the treatments, and the patients in the two groups were evaluated for their clinical efficacy and safety. Results: The overall response rate of the observation group was 66.67%. In terms of blood cells, the observation group's blood cell level after four courses of treatment was significantly higher than that of the control group ( Conclusions: AZA is safe and effective in the treatment of high risk MDS in middle and old age patients.

Indexed as

azacitidineefficacy evaluationmyelodysplastic syndromesretrospective study

Identifiers

PMID40181835
PMCPMC11967471

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.