Evidence map›Paper›PMID 40182587›Full record

ArticleFrontiers in digital health2025

Self-initiated humour protocol: a pilot study with an AI agent.

Abbas Edalat, Ruoyu Hu, Zeena Patel, Neophytos Polydorou, Frank Ryan, Dasha Nicholls

Abstract read
In one paragraph

Article in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abbas EdalatAlgorithmic Human Development Group, Department of Computing, Imperial College London, London, United Kingdom.
Ruoyu HuAlgorithmic Human Development Group, Department of Computing, Imperial College London, London, United Kingdom.
Zeena PatelAlgorithmic Human Development Group, Department of Computing, Imperial College London, London, United Kingdom.
Neophytos PolydorouAlgorithmic Human Development Group, Department of Computing, Imperial College London, London, United Kingdom.
Frank RyanFaculty of Medicine Centre, Faculty of Medicine, Imperial College London, London, United Kingdom.
Dasha NichollsDivision of Psychiatry, Faculty of Medicine, Imperial College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Non-hostile humour and laughter have been known for therapeutic benefits in an individual's mental health and wellbeing. To this end, we evaluated the Self-Initiated Humour Protocol (SIHP), a new type of self-administrable laughter intervention that utilises spontaneous and self-induced laughter. Rooted in the core principles of the Self-Attachment Technique-in which an individual creates an affectional bond with their childhood self as represented by their childhood photo or personalised childhood avatar-SIHP provides an algorithmic framework for individuals to learn to laugh in a non-hostile manner and develop a sense of humour in all possible life contexts. This allows SIHP to be self-administered by interacting with an AI agent. Methods: An 8-week intervention was conducted with N = 27 adult participants. Exclusion criteria: severe depression or anxiety (PHQ-9 and GAD-7 scores above 15). Participants' measurements were collected in the areas of wellbeing, use of different humour styles, emotional self-regulation, self-compassion and psychological capital, and analysed to understand any changes over time. Measurements were taken immediately before, after the intervention, and at the 3-month follow-up. Throughout the intervention, participants were required to practise SIHP 20 min a day with the aid of an emotionally intelligent chatbot and their personalised child avatar in virtual reality (VR). Results: Analysis of results at the 3-month follow-up showed significant improvements in the primary outcome of wellbeing with large effect size ( Discussion: This study shows the potential for the practice of SIHP as supported by an emotionally intelligent chatbot and personalised child avatar to have medium-term positive effects, which should be validated through future randomised trials.

Indexed as

chatbotemotion regulationself-attachmentself-compassionself-enhancing humourself-initiated humourvirtual realitywellbeing

Identifiers

PMID40182587
PMCPMC11965911

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.