Evidence map›Paper›PMID 40190016›Full record

ArticleGut microbes2025

Cross-feeding-based rational design of a probiotic combination of

Shanshan Qiao, Tao Wang, Jingzu Sun, Junjie Han, Huanqin Dai, Mengxuan Du, Lan Yang, Chun-Jun Guo, Chang Liu, Shuang-Jiang Liu and 1 more

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A novel exopolysaccharide fromGut microbes · 2026
    Article
  3. Article
  4. Foods (Basel, Switzerland) · 2026
    Article
  5. Alternating High-Fat and Polysaccharide Diets Modulates Gut Phage-Bacterial Interplay.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Apple Pomace Fermented with Non-International journal of molecular sciences · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Microorganisms · 2025
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shanshan QiaoState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.
Tao WangState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.
Jingzu SunState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.
Junjie HanState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.
Huanqin DaiState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.
Mengxuan DuState Key Laboratory of Microbial Technology, Shandong University, Qingdao, P. R. China.
Lan YangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, P. R. China.
Chun-Jun GuoJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Chang LiuState Key Laboratory of Microbial Technology, Shandong University, Qingdao, P. R. China.ORCID 0000-0001-9398-3701
Shuang-Jiang LiuState Key Laboratory of Microbial Technology, Shandong University, Qingdao, P. R. China.ORCID 0000-0002-7585-310X
Hongwei LiuState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.ORCID 0000-0001-6471-131X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiota has gained interest as an environmental factor that contributes to health or disease. The development of next-generation live biotherapeutic products (LBPs) is a promising strategy to modulate the gut microbiota and improve human health. In this study, we identified a novel cross-feeding interaction between

Indexed as

BacteroidesClostridium butyricumGastrointestinal MicrobiomeMetabolic DiseasesProbioticsAnimalsDiet, High-FatDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLObesityBacteroides xylanisolvensClostridium butyricumcross-feedingLBPlive biotherapeutic productsmetabolic disease

Identifiers

PMID40190016
PMCPMC11980479

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.