Evidence map›Paper›PMID 40190339›Full record

ArticleDigital health

The relationship between age and physical activity as objectively measured by accelerometers in older adults with and without dementia.

Karl Brown, Andrew Shutes-David, Sarah Payne, Adrienne Jankowski, Katie Wilson, Edmund Seto, Debby W Tsuang

Abstract read
In one paragraph

Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karl BrownGeriatric Research, Education, and Clinical Center, VISN-20, VA Puget Sound Health Care System, Seattle, WA, USA.ORCID https://orcid.org/0000-0001-8132-1196
Andrew Shutes-DavidGeriatric Research, Education, and Clinical Center, VISN-20, VA Puget Sound Health Care System, Seattle, WA, USA.ORCID https://orcid.org/0000-0003-2478-4391
Sarah PayneGeriatric Research, Education, and Clinical Center, VISN-20, VA Puget Sound Health Care System, Seattle, WA, USA.
Adrienne JankowskiGeriatric Research, Education, and Clinical Center, VISN-20, VA Puget Sound Health Care System, Seattle, WA, USA.
Katie WilsonGeriatric Research, Education, and Clinical Center, VISN-20, VA Puget Sound Health Care System, Seattle, WA, USA.
Edmund SetoDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.
Debby W TsuangGeriatric Research, Education, and Clinical Center, VISN-20, VA Puget Sound Health Care System, Seattle, WA, USA.

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Use of wearable sensors to improve the early diagnosis of DLBR33AG064271 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI TSUANG, DEBBY WEN · 2022 to 2024
$2.1M
Use of wearable sensors to improve the early diagnosis of DLBR21AG064271 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI TSUANG, DEBBY WEN · 2019 to 2020
$415k
NIA NIH HHS R21 AG064271NIA NIH HHS R33 AG064271NIA NIH HHS U01 AG032947NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

Objective: This study sought to investigate differences in physical activity and activity fragmentation between older adults with and without dementia and between older adults with dementia with Lewy bodies (DLB) and older adults with Alzheimer's disease (AD). The study also sought to investigate how these differences vary in magnitude at different ages. Methods: Accelerometry data were analyzed from individuals with dementia ( Results: In the NHATS cohort, individuals without dementia had more activity counts (0.325 million [95% CI 0.162 million, 0.487 million]) and a longer active bout length (0.631 minutes [95% CI 0.311, 0.952]) at the mean age of 79 than individuals with dementia at the same age. There was also suggestive evidence that individuals without dementia had a shorter resting bout length (-2.196 minutes [95% CI -4.996, 0.605]) than individuals with dementia. Differences in data collection and processing prevented direct comparisons between the cohorts, and the parallel analyses in the smaller cohort were underpowered to detect statistically significant differences between DLB and AD. Conclusion: This work shows that objectively measured accelerometry data differ between individuals with and without dementia; future studies with larger samples should investigate whether accelerometry data can be used to aid in the early identification of dementia and differentiation of dementia subtypes.

Indexed as

ActigraphyAlzheimer's diseasedementia with Lewy bodies

Identifiers

PMID40190339
PMCPMC11970097

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.