Evidence mapPaperPMID 40190707Full record

ReviewFrontiers in bioengineering and biotechnology2025

Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.

Mengqiang Hu, Bing Chen, Yuanming Luo

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mengqiang HuState Key Laboratory of Transvascular Implantation Devices, Hangzhou, China.
Bing ChenState Key Laboratory of Transvascular Implantation Devices, Hangzhou, China.
Yuanming LuoDepartment of Mechanical Engineering, The University of Iowa, Iowa City, IA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodynamic analysis based on computational fluid dynamics (CFD) modelling is expected to improve risk stratification for patients with aortic aneurysms and dissections. However, the parameter settings in CFD simulations involve considerable variability and uncertainty. Additionally, the exact relationship between hemodynamic features and disease progression remains unclear. These challenges limit the clinical application of aortic hemodynamic models. This review presents a detailed overview of the workflow for CFD-based aortic hemodynamic analysis, with a focus on recent advancements in the field. We also conducted a systematic review of 27 studies with large sample sizes (n > 5) that examine the hemodynamic characteristics of aortic aneurysms and dissections. Some studies identified consistent relationships between hemodynamic features and disease progression, reinforcing the potential for clinical application of aortic hemodynamic models. However, limitations such as small sample sizes and oversimplified patient-specific models remain. These findings emphasize the need for larger, more detailed studies to refine CFD modelling strategies, strengthen the connection between hemodynamics and diseases, and ultimately facilitate the clinical use of aortic hemodynamic models in disease management.

Indexed as

aortic aneurysmaortic dissectionCFDhemodynamicswall shear stress

Identifiers

PMID40190707
PMCPMC11968685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.