Evidence map›Paper›PMID 40190829›Full record

ReviewCureus2025

Micronutrients and the Periodontium: A Narrative Review.

Dhruvi Doshi, Santosh Kumar, Bhavin Patel, Dipak Chaudhari, Shirishkumar Patel, Tanvi Hirani, Hiren H Patadiya, Isha R Bhingradia, Mainul Haque

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dhruvi DoshiPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Santosh KumarPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Bhavin PatelPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Dipak ChaudhariPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Shirishkumar PatelPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Tanvi HiraniPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Hiren H PatadiyaGeneral Dentistry, My Dental Southbridge PLLC, Southbridge, USA.
Isha R BhingradiaPeriodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Mainul HaquePharmacology and Therapeutics, National Defence University of Malaysia, Kuala Lumpur, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a comprehensive narrative assessment of micronutrient relevance for periodontal health. The periodontium is a crucial and intricate structure that supports the tooth within the alveolar bone. Composed of four tissues with distinct embryological origins- the alveolar bone, cementum, gingiva, and periodontal ligament - the periodontium plays a fundamental role in maintaining dento-alveolar function and homeostasis. Periodontitis is gaining attention due to its widespread occurrence worldwide. This inflammatory condition disrupts the balance between the host immune response and microbial virulence factors. Connective tissue production and host defenses require proteins for periodontal health. Vegetable proteins support periodontal health by promoting tissue repair and immune function, while excessive dietary fats can exacerbate inflammation and increase the risk of periodontal disease (PD). Inflammation is further compounded due to dietary animal fats, which contribute to the risk of PD. Omega-3 fatty acids are well-known for their anti-inflammatory effects, which help reduce periodontal inflammation. Adequate intake of essential minerals and vitamins is required for maintaining periodontal health. Vitamins K, D, and A are crucial in maintaining oral epithelial integrity, facilitating bone development, and supporting overall tissue maintenance. Inadequate calcium (Ca²⁺) and magnesium (Mg²⁺) levels have been associated with severe PD. Antioxidants such as vitamin C help alleviate inflammation in periodontal tissues. As recognized by dental professionals, nutritional status plays a considerable role in an individual's risk of developing PD.

Indexed as

alpha tocopherolascorbic acidcalciferolscobalamin (b12)macronutrientsmicronutrientsmineralsperiodontal diseasephylloquinoneretinol

Identifiers

PMID40190829
PMCPMC11970441

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.