Evidence map›Paper›PMID 40190919›Full record

ReviewCureus2025

Exploring the Effects of Tirzepatide on Obstructive Sleep Apnea: A Literature Review.

Jimmy Wen, Denise Nadora, Alina Truong, Ethan Bernstein, Christiane How-Volkman, Daniel I Razick, Muzammil Akhtar, Adam A Razick, Eldo Frezza

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jimmy WenPhysical Medicine and Rehabilitation, California Northstate University College of Medicine, Elk Grove, USA.
Denise NadoraInternal Medicine, California Northstate University College of Medicine, Elk Grove, USA.
Alina TruongInternal Medicine, California Northstate University College of Medicine, Elk Grove, USA.
Ethan BernsteinOrthopedic Surgery, California Northstate University College of Medicine, Elk Grove, USA.
Christiane How-VolkmanCollege of Medicine, California Northstate University College of Medicine, Elk Grove, USA.
Daniel I RazickSurgery, California Northstate University College of Medicine, Elk Grove, USA.
Muzammil AkhtarSurgery, California Northstate University College of Medicine, Elk Grove, USA.
Adam A RazickPsychology, University of California Los Angeles, Los Angeles, USA.
Eldo FrezzaSurgery, California Northstate University College of Medicine, Elk Grove, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a sleep disorder commonly secondary to obesity that has detrimental effects on health and quality of life. Thus, weight loss is one of the mainstays of OSA treatment. Tirzepatide, a novel glucagon-like peptide-1 (GLP-1) and glucagon-dependent insulinotropic polypeptide (GIP) dual agonist, demonstrated significant glycemic control and weight loss. This literature review analyzes the current literature on tirzepatide's effects on OSA, mechanism of action, complications, and off-label uses/indications. Also, this review offers potential insights into how tirzepatide and other GLP-1 medications can be repurposed for other metabolic conditions and their associated sequelae.

Indexed as

glp-1 agonistobstructive sleep apneaosatirzepatideweight loss

Identifiers

PMID40190919
PMCPMC11972082

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.