Evidence map›Paper›PMID 40191220›Full record

ArticleJournal of radiology and clinical imaging2025

Uterine Artery Embolization: A Growing Pillar of Gynecological Intervention.

Sunil Balamurugan, Rahul Shah, Kurt Panganiban, Matthew Lehrack, Devendra K Agrawal

Abstract read
In one paragraph

Article in Journal of radiology and clinical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. CAR T-Cell Therapy in Cancer: Balancing Efficacy with Cardiac Toxicity Concerns.Journal of cancer science and clinical therapeutics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sunil BalamuruganDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.
Rahul ShahDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.
Kurt PanganibanDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.
Matthew LehrackDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.
Devendra K AgrawalDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.

Funding

Novel Molecular Target to Prevent Maturation Failure of Arteriovenous FistulaR01HL147662 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI AGRAWAL, DEVENDRA K. · 2019 to 2022
$2.8M
Research Education Program to Promote Diversity in Immunologic and Allergic DiseasesR25AI179582 · NIAID · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI Devendra K. Agrawal · 2025 to 2026
$756k
NHLBI NIH HHS R01 HL147662NIAID NIH HHS R25 AI179582
6 · The paper itself

Abstract

Uterine Artery Embolization (UAE) is a minimally invasive procedure that has emerged as a transformative option for managing uterine leiomyomas (fibroids), postpartum hemorrhage, and other gynecological conditions. While traditional surgical interventions like hysterectomy and myomectomy remain standard, UAE offers a safer alternative for patients seeking uterine preservation or fertility maintenance. This article examines the efficacy, innovations, and challenges of UAE, with a focus on its expanding applications and implications for patient care. Existing research highlights high success rates of UAE, achieving significant symptom relief in over 90% of cases by occluding uterine arterial blood supply with embolic agents to induce localized ischemia and fibroid necrosis. Innovations in embolic materials, such as hydrophobic injectable liquids, and procedural techniques like transradial access have enhanced safety, reduced complications, and improved patient outcomes. The effectiveness of UAE in treating rarer conditions, including uterine arteriovenous malformations and adenomyosis, demonstrates its versatility. However, questions remain about its long-term reproductive impact, especially concerning fertility outcomes and pregnancy rates, as conflicting data suggest potential risks. This critical review addresses these gaps by synthesizing existing studies to assess comparative efficacy of UAE against surgical options, its safety profile, and its role in advancing minimally invasive gynecology. By exploring both well-established and emerging applications, this article underscores the importance of UAE in reducing morbidity, improving quality of life, and preserving reproductive potential. Further research is essential to refine patient selection criteria, optimize techniques, and better understand the long-term outcomes of the procedure, ensuring UAE continues to evolve as a valuable minimally invasive option within modern gynecological care.

Indexed as

Cesarean Scar PregnancyEmbolic agentsFertility preservationGynecological interventionMinimally invasive procedureMyomectomyPostpartum hemorrhageUterine artery embolizationUterine CancerUterine fibroids

Identifiers

PMID40191220
PMCPMC11970953

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.