Evidence mapPaperPMID 40194976Full record

Observational studyJournal of the American Heart Association2025

Prognostic Value of Strain by Tissue Tracking Cardiac Magnetic Resonance in Myocardial Infarction With Nonobstructive Coronary Arteries.

Lei Chen, Bowen Qiu, Fuad A Abdu, Lu Liu, Wen Zhang, Chunyue Wang, Jiasuer Alifu, Penglong Qi, Wenliang Che, Yuan Lu

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06502899 (Prognostic Value of CMR-related Parameters in Patients with MINOCA), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06502899 completednot on this map

Prognostic Value of CMR-related Parameters in Patients with MINOCA

TypeobservationalSponsorThe Affiliated Hospital of Xuzhou Medical UniversityRan2019 to 2024Enrolled387ConditionsCardiac Magnetic Resonance, Myocardial Infarction with Nonobstructive Coronary Arteries, Strain, Extracellular VolumeArmsCardiac MRI
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lei ChenDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.ORCID 0000-0002-1498-718X
Bowen QiuDepartment of Cardiology The Affiliated Hospital of Xuzhou Medical University Xuzhou China.
Fuad A AbduDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.ORCID 0000-0002-3222-4709
Lu LiuDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.
Wen ZhangDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.
Chunyue WangDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.
Jiasuer AlifuDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.
Penglong QiDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.
Wenliang CheDepartment of Cardiology Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai China.
Yuan LuDepartment of Cardiology The Affiliated Hospital of Xuzhou Medical University Xuzhou China.ORCID 0000-0003-2716-4454

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStrain assessed by cardiac magnetic resonance (CMR) is a key prognostic indicator in myocardial infarction. However, the strain characteristics and prognostic value in myocardial infarction with nonobstructive coronary arteries (MINOCA) with different causes are unclear. This study aims to describe left atrial (LA) and left ventricular strain in patients with MINOCA and evaluate their predictive value for major adverse cardiovascular events (MACEs) in "true MINOCA" cases. METHODS AND

resultsThis single-center retrospective study included patients suspected of myocardial infarction who completed CMR during hospitalization. CMR images were used to obtain LA and left ventricular strain via CMR feature tracking. True MINOCA was defined by evidence of ischemia or infarction on CMR. MACEs included all-cause death, recurrent myocardial infarction, stroke, heart failure, atrial fibrillation, and angina pectoris. This study included 386 patients, with a median time from admission to CMR of 4 days. LA and left ventricular strains varied by pathogenesis, with the lowest strain in patients with cardiomyopathy. For patients with true MINOCA, Cox regression showed that global longitudinal strain (hazard ratio [HR], 0.90 [95% CI, 0.82-0.99];

conclusionsLA and left ventricular strains vary among MINOCA pathogeneses. In true MINOCA patients, global longitudinal strain and LA reservoir strains independently predict MACE risk. Integrating these strains enhances MACE prediction. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique Identifier: NCT06502899.

Indexed as

Atrial Function, LeftCoronary VesselsMagnetic Resonance Imaging, CineMINOCAMyocardial InfarctionVentricular Function, LeftAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective Studiescardiac magnetic resonanceleft atrial strainleft ventricular strainmajor adverse cardiac eventsMINOCA

Identifiers

PMID40194976
PMCPMC12132887

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.