ArticleCancer management and research2025
Interventional Treatment Strategies for Carotid Blowout Syndrome After Radiotherapy for Nasopharyngeal Carcinoma.
Article in Cancer management and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Primary endoscopic nasopharyngectomy for nasopharyngeal carcinoma: systematic review & meta-analysis.Frontiers in surgery · 2026Pooled it
- Case report: Emergency management of adjacent arterial injury during inferior vena cava angioplasty in a patient with Budd-Chiari syndrome.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Carotid blowout syndrome (CBS) is a life-threatening complication that can occur after radiotherapy in nasopharyngeal carcinoma (NPC) patients, resulting in catastrophic hemorrhage. Endovascular treatments, including coil embolization and stent grafting, have become standard options for managing CBS. Recent studies suggest that individualized approaches based on aneurysm location and vascular condition may further reduce recurrence and complications. This study aims to evaluate the efficacy, safety, and outcomes of these treatments in NPC patients with CBS. Methods: A retrospective analysis was conducted on 46 NPC patients who developed CBS following radiotherapy and underwent endovascular intervention at Zhongshan People's Hospital between January 2016 and July 2023. Outcomes such as immediate hemostasis, rebleeding rates, complications, and 1-year survival were analyzed. Results: Among the 46 patients, 29 received coil embolization and 17 underwent stent grafting. Immediate hemostasis was achieved in all cases (100%). The 1-year rebleeding rate was 8.6% (4/46), and the overall complication rate was 8.6% (4/46), with cerebral infarctions being the primary concern. Coil embolization is associated with lower rebleeding rates, while stent grafting preserves arterial patency better. The 1-year survival rate was 89.1% (41/46). Conclusion: Endovascular interventions, including coil embolization and stent grafting, are effective in managing CBS in NPC patients after radiotherapy. Future research should focus on refining patient selection criteria and optimizing long-term outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.