Evidence map›Paper›PMID 40196870›Full record

ArticleOncoTargets and therapy2025

Anti-Tumor Effects of Gilteritinib on

Taisuke Nakazawa, Hirofumi Tsuzuki, Tatsuya Kawase, Masamichi Mori, Taku Yoshida

Abstract read
In one paragraph

Article in OncoTargets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taisuke NakazawaAstellas Pharma Inc, Ibaraki, Japan.ORCID 0009-0007-0222-9609
Hirofumi TsuzukiAstellas Pharma Inc, Ibaraki, Japan.
Tatsuya KawaseAstellas Pharma Inc, Ibaraki, Japan.
Masamichi MoriAstellas Pharma Inc, Ibaraki, Japan.
Taku YoshidaAstellas Pharma Inc, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The efficacy of Fms-like tyrosine kinase 3 (FLT3) inhibitors has been well established against acute myeloid leukemia (AML) with Methods: This study examined the inhibitory effects of gilteritinib, quizartinib and midostaurin on Ba/F3 cells with Results: Gilteritinib showed similar or superior growth inhibition against the majority of Conclusion: These findings highlight the potent efficacy of gilteritinib against a wide range of

Indexed as

acute myeloid leukemiadrug resistanceFLT3-JMDFLT3-TKDgilteritinibxenograft mouse models

Identifiers

PMID40196870
PMCPMC11974573

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.