Observational studyBMC cardiovascular disorders2025
Global trends and regional disparities in atrial fibrillation and flutter burden attributable to high alcohol consumption: findings from the global burden of disease study 2021.
Observational study in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Trends in the Disease Burden of Migraine Among Women of Reproductive Age (15-49 Years) in Low- and Middle-Income Countries, 1990-2023.International journal of women's health · 2026Article
- Burden of atrial fibrillation and atrial flutter attributable to smoking in the G20: Trends from 1990 to 2021 and predictions for 2022 to 2050: A secondary dataset analysis of the Global Burden of Disease (GBD) 2021.Tobacco induced diseases · 2026Article
- Global burden of motor neuron disease: unraveling socioeconomic disparities, aging dynamics, and divergent future trajectories (1990-2040).Journal of neurology · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the global burden of atrial fibrillation (AF) and atrial flutter (AFL) attributable to high alcohol consumption (HAC) from 1990 to 2021, and to examine its spatiotemporal distribution characteristics. STUDY
designAn observational study based on Global Burden of Disease Study (GBD) 2021 data.
methodsUsing GBD 2021 data, we analyzed trends in disability-adjusted life years (DALYs) and mortality for AF/AFL attributable to HAC at the global, regional, and national levels from 1990 to 2021, with a focus on differences by gender, age, and socio-demographic index (SDI).
resultsDALYs for HAC-attributable AF/AFL rose from 155,703 (95% UI: 105,255-206,083) in 1990 to 362,698 (95% UI: 263,321-465,594) in 2021, while mortality increased from 4,308 (95% UI: 3,000-5,597) to 11,908 (95% UI: 7,826-30,753). Males and individuals aged ≥ 60 years experienced the highest burdens. Australasia recorded the highest DALYs and mortality in 2021, while South Asia showed the steepest increases, with EAPCs of 2.95 and 4.18, respectively. Higher SDI regions showed greater burdens, peaking at an SDI of 0.8 before declining.
conclusionsHAC contributes significantly to the global AF/AFL burden, with marked regional and demographic disparities. Targeted interventions are urgently needed to address this growing public health challenge.
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