Evidence map›Paper›PMID 40198839›Full record

Observational studyEndocrinology, diabetes & metabolism2025

Long-Term Performance of Two Systems for Automated Insulin Delivery in Adults With Type 1 Diabetes: An Observational Study.

Sanne Fisker, Mia Christensen, Ermina Bach, Bo Martin Bibby, Klavs Würgler Hansen

Abstract readObservational StudyComparative Study
In one paragraph

Observational study in Endocrinology, diabetes & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sanne FiskerSteno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Mia ChristensenMedical Diagnostic Center, Silkeborg Regional Hospital, Silkeborg, Denmark.ORCID 0009-0002-6344-1260
Ermina BachSteno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Bo Martin BibbySection for Biostatistics, Department of Public Health, Aarhus University, Aarhus, Denmark.
Klavs Würgler HansenMedical Diagnostic Center, Silkeborg Regional Hospital, Silkeborg, Denmark.ORCID 0000-0002-7452-2747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo compare glycaemic outcomes for two automated insulin delivery (AID) systems, the Tandem Control IQ (CIQ) and the MiniMed 780G (MM780G). MATERIAL AND

methodsIn this observational study, we evaluated 60 days of glycaemic data from 139 persons with type 1 diabetes (CIQ: 79 persons, MM780G: 60 persons), who had an active glucose sensor time ≥ 85%.

resultsThe time with AID was median 620 (IQR, 439-755) days for CIQ users and 509 (429-744) days for MM780G users (p = 0.26). The last HbA1c before initiation of AID was 59.7 mmol/mol in CIQ and 60.1 mmol/mol in MM780G (p = 0.88). The time with an active glucose sensor was higher for CIQ than MM780G (median 98.5 (97.4-98.0)% vs. 96.5 (94.9-97.0)%, p < 0.001). Time in range (TIR, glucose 3.9-10.0 mmol/L) was lower in CIQ than MM780G (mean 68.9% ± 11.4% vs. 73.7% ± 12.0%, p = 0.02) as was time in tight range (TITR) (glucose 3.9-7.8 mmol/L) (43.0% ± 12.2% vs. 48.4% ± 12.7%, p = 0.01). The difference in TIR (4.2 (95% CI 1.0-7.5)%, p = 0.01) and TITR (5.0 (1.4-8.6)%, p < 0.01) remained statistically significant in a multiple regression model controlling for various baseline variables. Time with an absolute rate of glucose change > 1.5 mmol/L/15 min was higher in CIQ than MM780G (9.4 (IQR, 7.2-13.3)% vs. 7.4 (5.2-10.4)%, p < 0.001).

conclusionsThe CIQ system had a higher active glucose sensor time but a lower TIR, TITR, and a higher time with a rapid glucose rate of change than the MM780G system.

Indexed as

Diabetes Mellitus, Type 1Hypoglycemic AgentsInsulinInsulin Infusion SystemsAdultBlood GlucoseBlood Glucose Self-MonitoringFemaleGlycated HemoglobinGlycemic ControlHumansMaleMiddle AgedBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinautomated insulin deliverycontinuous glucose monitoringglucose rate of changeglucose time in rangetype 1 diabetes

Identifiers

PMID40198839
PMCPMC11977919

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.