Evidence map›Paper›PMID 40200134›Full record

ArticleBMC plant biology2025

A multi-omics analysis reveals candidate genes for Cd tolerance in Paspalum vaginatum.

Xu Hu, Ling Pan, Chunchan Fu, Qing Zhu, Jiangshan Hao, Xiaochun Wang, Mohsin Nawaz, Jia Qu, Jinlin Zhang, Yu Chen and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xu Hu *College of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China.
Ling Pan *College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Chunchan Fu *College of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China.
Qing ZhuCollege of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China.
Jiangshan HaoSchool of Agriculture, Jinhua Polytechnic, Jinhua, 321016, China.
Xiaochun WangCollege of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China.
Mohsin NawazInstitute of Environment and Ecology, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, China.
Jia QuCollege of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China.
Jinlin ZhangState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystem, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730000, China.
Yu ChenCollege of Agro-Grassland Science, Nanjing Agricultural University, Nanjing, 210095, China.
Junqin ZongInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Li LiaoCollege of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China. liaoli@hainanu.edu.cn.
Minqiang TangCollege of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China. tangminqiang@hainanu.edu.cn.
Zhiyong WangCollege of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572000, China. wangzhiyong@hainanu.edu.cn.

Funding

Collaborative Innovation Center Project of Ecological Civilization in Hainan University XTCX2022STC10Collaborative Innovation Center Project of Nanfan and High-Efficiency Tropical Agriculture in Hainan University XTCX2022NYB08Hainan Natural Science Foundation high-level Talents Project No.321RC475Innovational Fund for Scientific and Technological Personnel of Hainan Province KJRC2023C21the Hainan Province Science and Technology Special Fund ZDYF2023XDNY078the National Natural Science Foundation of China No.32060409
6 · The paper itself

Abstract

Cadmium (Cd) pollution in the farmland has become a serious global issue threatening both human health and plant biomass production. Seashore paspalum (Paspalum vaginatum Sw.), a halophytic turfgrass, has been recognized as a Cd-tolerant species. However, the underlying genetic basis of natural variations in Cd tolerance still remains unknown. This study is possibly the first to apply genome-wide association studies (GWAS) and selective sweep analysis to identify potential Cd stress-responsive genes in P. vaginatum. We identified a total of 89 candidate genes and 656 putative selective sweeps regions. Based on the correlation analysis of differentially expressed metabolites (DEMs) and differentially expressed genes (DEGs), we identified the 55 key genes associated with metabolic changes induced by Cd treatment as the Cd tolerance-related genes. These genes showed significantly higher expression in Cd-tolerant accessions as compared to Cd-susceptive accessions. Therefore, our multi-omics study revealed the molecular and genetic basis of Cd tolerance, which may help develop Cd tolerant crop varieties.

Indexed as

CadmiumGenes, PlantPaspalumGene Expression Regulation, PlantGenome-Wide Association StudyMultiomicsCadmiumCadmium stress responsiveGenome-wide association studyMetabolomePaspalum vaginatumTranscriptome

Identifiers

PMID40200134
PMCPMC11978127

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.