Evidence mapPaperPMID 40200219Full record

SynthesisBMC musculoskeletal disorders2025

Effects of exercise in older adults with osteosarcopenic adiposity: a systematic review and meta-analysis of randomized controlled trials.

Lei Chen, Wenlu Zhou, Ju Li, Taotao Xu, Zhenyu Shi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lei Chen *The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang Province, 310053, China.
Wenlu Zhou *Zhejiang Chinese Medical University, 548 Binwen Road, Hangzhou, Zhejiang Province, 310006, China.
Ju LiThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang Province, 310053, China.
Taotao XuThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang Province, 310053, China.
Zhenyu ShiThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang Province, 310053, China. shizhenyu0930@163.com.

Funding

National Natural Science Foundation of China 82205146National Natural Science Foundation of Zhejiang Province LQ23H270011National Natural Science Foundation of Zhejiang Province LY24H270001Traditional Chinese Medicine Science and Technology Program of Zhejiang Province 2023ZL367
6 · The paper itself

Abstract

aimTo evaluate the effects of exercise training on patients with osteosarcopenic adiposity (OSA).

methodsA comprehensive search was conducted in PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases for randomized controlled trials (RCTs) on exercise treatment for OSA patients. The search included both Chinese and English literature up to April 2024. Reference lists and grey literature were also reviewed. Two researchers independently screened the literature, extracted data, and assessed the quality of included studies. Meta-analysis was performed using RevMan 5.4 software.

resultsA total of 7 studies were included in this meta-analysis. Exercise interventions significantly improved bone mineral density (BMD) (MD = 0.0195, 95% CI: 0 to 0.02, P = 0.03), body fat (BF) (MD = -4.0, 95% CI: -5.46 to -2.54, P < 0.01), and hand grip strength (HGS) (MD = 3.13, 95% CI: 0.72 to 5.54, P = 0.01) in patients with OSA. However, no significant differences were observed in skeletal muscle mass index (SMI) (MD = 0.12, 95% CI: -0.26 to 0.50, P = 0.55), gait speed (GS) (SMD = 0.75, 95% CI: -1.26 to 2.76, P = 0.47), or C-reactive protein (CRP) (MD = -0.23, 95% CI: -0.90 to 0.44, P = 0.50).

conclusionExercise interventions can effectively improve clinical symptoms and signs in OSA patients to varying degrees, highlighting the importance of exercise in the management of OSA.

Indexed as

AdiposityExerciseExercise TherapySarcopeniaAgedBone DensityHand StrengthHumansRandomized Controlled Trials as TopicTreatment OutcomeAdiposityExerciseOsteoporosisOsteosacopeniaRandomized controlled trialSarcopenia

Identifiers

PMID40200219
PMCPMC11980054

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.