Evidence map›Paper›PMID 40200316›Full record

ReviewBMC global and public health2025

Overview of foodborne hazards associated with inflammation and metabolic health.

Srishti Sinha, Laura S Hackl, Samantha L Huey, Elisabetta Lambertini, Stella Nordhagen, Anna M Bennett, Nidhi Shrestha, Nathaniel L Cole, Julia L Finkelstein, Saurabh Mehta

Abstract readReview
In one paragraph

Review in BMC global and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Microorganisms · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Srishti Sinha *Cornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA.
Laura S Hackl *Division of Nutritional Sciences, Cornell University, Ithaca, NY, 14853, USA.
Samantha L HueyCornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA.
Elisabetta LambertiniGlobal Alliance for Improved Nutrition, Washington, DC, 20036, USA.
Stella NordhagenGlobal Alliance for Improved Nutrition, Geneva, Switzerland.
Anna M BennettCornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA.
Nidhi ShresthaCornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA.
Nathaniel L ColeCornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA.
Julia L FinkelsteinCornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA.
Saurabh MehtaCornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, 3101 Martha van Rensselaer Hall, Ithaca, NY, 14853, USA. smehta@cornell.edu.

Funding

TRAINING IN MATERNAL AND CHILD NUTRITIONT32HD087137 · NICHD · CORNELL UNIVERSITY · PI Laura Bellows, Julia L. Finkelstein · 2016 to 2026
$2.0M
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5T32HD087137Feed The Future through the U.S. Agency for International Development (USAID) #7200AA19CA00010NICHD NIH HHS T32 HD087137
6 · The paper itself

Abstract

Access to safe and nutritious food is key to ensuring health and well-being and is critical to meeting the United Nations' Sustainable Development Goals. However, a synthesis of the associations between foodborne illness and malnutrition, such as metabolic health, remains a gap in the literature base. In this review, we summarized existing evidence on the impacts of biological and chemical hazards on nutrition-related health outcomes, specifically overweight and obesity, inflammation, metabolic disease, thyroid function, cancer development, and adverse birth outcomes, examining physiological mechanisms, epidemiological associations, and animal studies. Mechanisms between some foodborne hazards, such as H. pylori, and adverse pregnancy outcomes, e.g., gestational diabetes mellitus, or between nitrates and impaired thyroid function, are relatively well-studied. However, evidence on the effects of many other chemical hazards on metabolic and human health remains limited: for example, while arsenic exposure is associated with adverse birth outcomes, the limited availability of dose-response studies and other challenges limit ascertaining its causal role. Untangling these associations and physiological mechanisms is of high relevance for both high- as well as low- and middle-income countries. Emerging technologies and novel assessment techniques are needed to improve the detection and understanding of understudied and complex foodborne diseases, particularly those arising from chemical hazards. These evidence gaps are highlighted in this review, as well as the need for establishing surveillance systems for monitoring foodborne diseases and metabolic health outcomes across populations.

Indexed as

Biological hazardsChemical hazardsFoodborne diseaseMetabolic healthNutrition

Identifiers

PMID40200316
PMCPMC11980346

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.