Evidence map›Paper›PMID 40200344›Full record

ArticleBMC medical education2025

The potential of artificial intelligence reading label system on the training of ophthalmologists in retinal diseases, a multicenter bimodal multi-disease study.

Meng Wang, Xiao Zhang, Donghui Li, Qijie Wei, Jianchun Zhao, Xiang Gao, Tianhui Shan, Hao Feng, Guolong Ding, Chan Li and 4 more

Abstract readMulticenter Study
In one paragraph

Article in BMC medical education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Meng WangDepartment of Ophthalmology, Peking Union Medical College Hospital, No. 1 Shuaifu Yuan, Dongcheng District, Beijing, 100730, China.
Xiao ZhangDepartment of Ophthalmology, Peking Union Medical College Hospital, No. 1 Shuaifu Yuan, Dongcheng District, Beijing, 100730, China.
Donghui LiDepartment of Ophthalmology, Peking Union Medical College Hospital, No. 1 Shuaifu Yuan, Dongcheng District, Beijing, 100730, China.
Qijie WeiMoE Key Lab of DEKE, Renmin University of China, Beijing, China.
Jianchun ZhaoVistel AI Lab, Visionary Intelligence Ltd, Beijing, China.
Xiang GaoEye Hospital of Shandong First Medical University, Jinan, Shandong, China.
Tianhui ShanEye Hospital of Shandong First Medical University, Jinan, Shandong, China.
Hao FengDepartment of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, Liaoning Province, China.
Guolong DingDepartment of Ophthalmology, Xi'an No. 1 hospital, Xi'an, China.
Chan LiDepartment of Ophthalmology, Xi'an No. 1 hospital, Xi'an, China.
Binghui WuDepartment of Ophthalmology, Xi'an No. 1 hospital, Xi'an, China.
Xirong LiMoE Key Lab of DEKE, Renmin University of China, Beijing, China.
Chan WuDepartment of Ophthalmology, Peking Union Medical College Hospital, No. 1 Shuaifu Yuan, Dongcheng District, Beijing, 100730, China. wuchan@pumch.cn.
Weihong YuDepartment of Ophthalmology, Peking Union Medical College Hospital, No. 1 Shuaifu Yuan, Dongcheng District, Beijing, 100730, China. yuweihongpumch@163.com.

Funding

National High Level Hospital Clinical Research Funding 2022-PUMCH-C-061
6 · The paper itself

Abstract

objectiveTo assess the potential of artificial intelligence reading label system on the training of ophthalmologists in a multicenter bimodal multi-disease study.

methodsThe accuracy of 16 ophthalmologists with study duration ranging from one to nine years across multiple annotation rounds and its correlation with the number of rounds and ophthalmology study duration were analyzed. Additionally, this study evaluated the concordance between optical coherence tomography (OCT) or color fundus photography (CFP) and final case diagnosis.

resultsThe study involved 7777 pairs of OCT and CFP images, cases labeled with nine prevalent retinal diseases including diabetic retinopathy (DR, 2118 cases), retinal detachment (RD, 121 cases), retinal vein occlusion (RVO, 886 cases), dry age-related macular degeneration (dAMD, 549 cases), wet age-related macular degeneration (wAMD, 1023 cases), epiretinal membrane (ERM, 1061 cases), central serous retinopathy (CSC, 150 cases), macular schisis (MS, 128 cases), macular hole (MH, 86 cases) and normal fundus (1036 cases) were selected for further analysis. All images were assigned to 16 ophthalmologists over five rounds. The average diagnostic accuracy for the nine retinal diseases and normal fundus improved significantly across the five rounds (p = 0.013) and is closely correlated to the duration of ophthalmology study (p = 0.007). Furthermore, significant improvements were observed in the diagnostic accuracy of both OCT (p = 0.028) and CFP (p = 0.021) modalities as the number of rounds increased. Notably, OCT single modal diagnosis demonstrated higher consistency with the final diagnosis in cases of RD, ERM, MS, and MH compared to CFP, while CFP single modal diagnosis has higher consistency in DR, RVO and normal fundus.

conclusionThe implementation of an artificial intelligence reading label system enhances the diagnostic accuracy of retinal diseases among ophthalmologists and holds potential for integration into future medical education.

Indexed as

Artificial IntelligenceOphthalmologistsOphthalmologyRetinal DiseasesHumansTomography, Optical CoherenceArtificial intelligenceDiagnostic accuracyMedical educationReading label systemRetinal diseases

Identifiers

PMID40200344
PMCPMC11980151

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.