Evidence map›Paper›PMID 40200774›Full record

ArticleInternational journal of fertility & sterility2025

Association of Genetic Variations in The PIK3-AKT-mTOR Pathway with Endometriosis Susceptibility: A Preliminary Case-Control Study.

Rahele Ghasemian Moghadam, Forough Forghani, Danial Jahantigh, Saeedeh Ghazaey Zidanloo, Mahnaz Rezaei, Mohsen Taheri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of fertility & sterility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rahele Ghasemian MoghadamDepartment of Obstetrics and Gynecology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Forough ForghaniDepartment of Obstetrics and Gynecology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. Email: f.forghani@zaums.ac.ir.
Danial JahantighDepartment of Biology, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran. Email: danial_jahantigh@science.usb.ac.ir.
Saeedeh Ghazaey ZidanlooDepartment of Cell and Molecular Biology, Kosar University of Bojnord, Bojnord, Iran.
Mahnaz RezaeiDepartment of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Mohsen TaheriGenetics of Non-Communicable Disease Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometriosis is a complex, heterogeneous disease with several genetic and non-genetic pathogenic factors. The phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway may influence both progression and different stages of endometriosis. This study aims to investigate the effects of the MATERIALS AND

methodsIn this case-control study, samples from 127 patients and 125 controls were examined using allelespecific polymerase chain reaction (AS-PCR) polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).

resultsThe

conclusionThe results show that

Indexed as

EndometriosisGene polymorphismsPhosphatidylinositol 3-KinasesTOR Serine-Threonine Kinases

Identifiers

PMID40200774
PMCPMC11976888

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.