ReviewJournal of dental anesthesia and pain medicine2025
The efficacy of sweet solutions on dental injection related pain: a systematic review of randomized controlled trials.
Review in Journal of dental anesthesia and pain medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral flavored solutions are effective for pain management. The intraoral application of sweet solutions at the injection site or on the tongue before local anesthetic administration leads to lower self-perceived pain than any other intervention. This systematic review aimed to evaluate the effect of sweet taste on injection pain in patients undergoing dental procedures. This systematic review was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD42024571962 and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). An initial electronic search without a time limit up to September 2024 revealed 1,087 studies from indexed databases (PubMed, Scopus, Embase, Cochrane, and Web of Science). The Cochrane Bias Assessment Tool was used to evaluate the risk of bias. After eliminating duplicate and automated records, 103 studies were screened for inclusion. After reviewing the titles and abstracts and assessing the eligibility of the studies, three were excluded and eight RCTs were considered appropriate for inclusion and analysis. This review highlights that all the included studies reported significantly reduced pain perception after sweet solutions, regardless of the specific type or concentration.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.