Evidence map›Paper›PMID 40201399›Full record

ArticleKidney medicine2025

Peritoneal Dialysis in Young Adults: A Mixed-Methods Study.

Hannah C Lyons, Lucy E Selman, Yoav Ben-Shlomo, Fergus J Caskey, Carol D Inward, Alexander Hamilton

Abstract read
In one paragraph

Article in Kidney medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Hannah C LyonsPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Lucy E SelmanPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Yoav Ben-ShlomoPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Fergus J CaskeyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Carol D InwardPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Alexander HamiltonPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peritoneal dialysis (PD) preserves kidney function and offers flexibility; however, few young adults have it compared with hemodialysis (HD). This study aimed to understand factors influencing the change from PD to HD. Study Design: This was a sequential explanatory mixed-methods study. Setting & Participants: Quantitative data were collected from 470 participants (50% male participants, 85% White, mean age: 16 years) who received dialysis between 1987 and 2015. Cox proportional hazards analysis was used to examine psychosocial factors associated with transitions from PD to HD. Qualitative data were gathered from 13 young adults (aged 14-29 years) who received dialysis between 2013 and 2015, with retrospective interviews conducted in 2020. Results: 25% of participants experienced multiple episodes of PD. Survival rates for PD at 1 and 5 years were 71% and 37%, respectively. Risk factors for transitioning to HD included young adulthood (age: 15-30 years), with higher transition risks in older age groups (age: 15-19 years, HR: 2.41; age: 20-24 years, HR: 3.39; age: 25-30 years, HR: 3.14; Limitations: The study was based on cross-sectional psychosocial data, lacked detailed parental involvement, and may have suffered recall bias. Conclusions: Young adults are at higher risk of transitioning to HD owing to both transplant failure and complications with PD. Challenges of PD have been underestimated, and there is a need to educate young adults well on all dialysis options. Additional support including mental health support, peer support, and support during life changes, such as moving out of their family home, is recommended.

Indexed as

Chronic kidney diseaseHaemodialysisPeritoneal dialysisYoung adults

Identifiers

PMID40201399
PMCPMC11978335

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.