Evidence map›Paper›PMID 40201803›Full record

ArticleOpen veterinary journal2025

Effects of probiotic supplementation on clinicopathological alterations in Barki sheep with Mange.

Asmaa A Darwish

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Asmaa A DarwishAnimal Health and Poultry Department, Animal Production and Poultry Division, Desert Research Center (DRC), Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ovine mange is a highly transmissible skin condition that typically results in significant economiclosses. Aim: This research explored the clinicopathological alterations associated with mange in Barki sheep and evaluated the impact of integrating probiotics (ZAD) into the treatment protocol. Additionally, the study proposed diagnostic markers and indicators for assessing treatment prognosis. Method: Twenty healthy lambs [control group (CG)] and 20 lambs suffered from mange symptoms (confirmed by skin scrapings) in the diseased group (DG). DG was divided into two groups: the traditional group (TG) was injected once with 1 ml/50 kg ivermectin 1% (Promectine, Invesa) subcutaneously injected + topical Zinc ointment, and the ZAD Group (ZG): received the same treatment + 5 ml/ head of ZAD orally, repeated daily for 3 weeks. Skin scraping was repeated weekly until complete curing in both groups. Blood samples were collected from CG, DG (before treatment), and TG and ZG (after recovery). Result: DG (compared to CG) showed a significant ( Conclusion: Ovine scabies can lead to systemic and clinicopathological changes, necessitating careful monitoring and intervention. Adding ZAD to the treatment of mangy sheep might help enhance their body weights and serum glucose levels, but it does not affect the healing or reduction of lesions. TAC and IL-1β serve as dependable indicators for diagnosing ovine scabies, whereas TAC and ferritin are valuable for evaluating treatment effectiveness.

Indexed as

ProbioticsSheep DiseasesAnimalsDietary SupplementsFemaleMaleSheepClinicopathological changesCytokinesHormonesMMPsOvine ScabiesOxidative stressProbiotics

Identifiers

PMID40201803
PMCPMC11974297

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.