Evidence map›Paper›PMID 40205039›Full record

ArticleNature2025

Human assembloid model of the ascending neural sensory pathway.

Ji-Il Kim, Kent Imaizumi, Ovidiu Jurjuț, Kevin W Kelley, Dong Wang, Mayuri Vijay Thete, Zuzana Hudacova, Neal D Amin, Rebecca J Levy, Grégory Scherrer and 1 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Using Brain Organoids to Explore Human Neurobiology.Cellular and molecular neurobiology · 2026
    Review
  8. Building and regenerating intestines by manipulating intestinal stem cells.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. New developments and applications of human organoids.Nature reviews. Molecular cell biology · 2026
    Review
  18. Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Ji-Il Kim *Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5710-7090
Kent Imaizumi *Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-3565-5248
Ovidiu JurjuțDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Kevin W KelleyDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Dong WangDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Mayuri Vijay TheteDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Zuzana HudacovaDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Neal D AminDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Rebecca J LevyDepartment of Neurology & Neurological Sciences, Division of Child Neurology, Stanford University, Stanford, CA, USA.
Grégory ScherrerDepartment of Cell Biology and Physiology, UNC Neuroscience Center, Department of Pharmacology, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0002-1983-5126
Sergiu P PașcaDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. spasca@stanford.edu.ORCID 0000-0002-3216-3248

Funding

Gaining insight into psychiatric disease by engineering piece by piece the human brain in vitro.R01MH107800 · NIMH · STANFORD UNIVERSITY · PI PASCA, SERGIU · 2015 to 2024
$5.6M
Defining and perturbing gene regulatory dynamics in the developing human brainR01NS128028 · NINDS · STANFORD UNIVERSITY · PI William James Greenleaf · 2023 to 2026
$2.4M
NIMH NIH HHS R01 MH107800NINDS NIH HHS R01 NS128028
6 · The paper itself

Abstract

Somatosensory pathways convey crucial information about pain, touch, itch and body part movement from peripheral organs to the central nervous system

Indexed as

Neural PathwaysOrganoidsSensory Receptor CellsAnimalsCalciumHumansMalePainPluripotent Stem CellsSomatosensory CortexSpinal CordThalamusTranscriptomeCalcium

Identifiers

PMID40205039
PMCPMC12137141

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.