Evidence map›Paper›PMID 40205498›Full record

ReviewJournal of translational medicine2025

Fluorescent probes in autoimmune disease research: current status and future prospects.

Junli Chen, Mingkai Chen, Xiaolong Yu

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Junli ChenWujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China.
Mingkai ChenWujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China.
Xiaolong YuWujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China. yuxiaolong@wjrmyy.cn.ORCID http://orcid.org/0009-0005-6001-6738

Funding

Changzhou High-Level Medical Talents Training Project 2022CZBJ109Open project of Jiangsu Key Laboratory of Laboratory Medicine JSKLM-Y-2024-003
6 · The paper itself

Abstract

Autoimmune diseases (AD) present substantial challenges for early diagnosis and precise treatment due to their intricate pathogenesis and varied clinical manifestations. While existing diagnostic methods and treatment strategies have advanced, their sensitivity, specificity, and real-time applicability in clinical settings continue to exhibit significant limitations. In recent years, fluorescent probes have emerged as highly sensitive and specific biological imaging tools, demonstrating substantial potential in AD research.This review examines the response mechanisms and historical evolution of various types of fluorescent probes, systematically summarizing the latest research advancements in their application to autoimmune diseases. It highlights key applications in biomarker detection, dynamic monitoring of immune cell functions, and assessment of drug treatment efficacy. Furthermore, this article analyzes the technical challenges currently encountered in probe development and proposes potential directions for future research. With ongoing advancements in materials science, nanotechnology, and bioengineering, fluorescent probes are anticipated to achieve higher sensitivity and enhanced functional integration, thereby facilitating early detection, dynamic monitoring, and innovative treatment strategies for autoimmune diseases. Overall, fluorescent probes possess substantial scientific significance and application value in both research and clinical settings related to autoimmune diseases, signaling a new era of personalized and precision medicine.

Indexed as

Autoimmune DiseasesBiomedical ResearchFluorescent DyesAnimalsBiomarkersHumansBiomarkersFluorescent DyesAutoimmune diseaseEarly diagnosisFluorescent probeMultimodal imagingNanotechnologyPrecision medicine

Identifiers

PMID40205498
PMCPMC11984237

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.