Evidence map›Paper›PMID 40206490›Full record

ArticleJournal of bone oncology2025

Pain in patients with multiple inherited osteochondromas: Incidence and potential prognostic factors. A retrospective cohort study.

Morena Tremosini, Mattia Morri, Cristiana Forni, Elena Pedrini, Marina Mordenti, Maria Gnoli, Alessia Di Cecco, Alice Moroni, Luca Sangiorgi

Abstract read
In one paragraph

Article in Journal of bone oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Morena TremosiniServizio di Assistenza Infermieristica Tecnica e Riabilitativa, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Mattia MorriServizio di Assistenza Infermieristica Tecnica e Riabilitativa, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Cristiana ForniServizio di Assistenza Infermieristica Tecnica e Riabilitativa, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Elena PedriniStruttura Complessa Malattie Rare Scheletriche, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Marina MordentiStruttura Complessa Malattie Rare Scheletriche, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Maria GnoliStruttura Complessa Malattie Rare Scheletriche, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Alessia Di CeccoServizio di Assistenza Infermieristica Tecnica e Riabilitativa, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Alice MoroniStruttura Complessa Malattie Rare Scheletriche, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Luca SangiorgiStruttura Complessa Malattie Rare Scheletriche, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: the purpose of this study was to describe the baseline characteristics, presenting phenotype and treatment interventions for patients diagnosed with multiple osteochondromas who presented with severe pain symptoms. Methods: a retrospective single-centre cohort study was conducted at a Rare Skeletal Disorders Department. Pain symptomatology was measured at the first visit, pain level was reported, varying from 0, absence of pain to 10, maximum pain. Baseline characteristics, pathology phenotype using IOR classification and treatments performed/ongoing as medical, surgical and conservative therapies were collected. Results: a total of 152 patients were enrolled, with a median pain score of 0 and the 25th and 75th percentiles of 0 and 4, respectively. A percentage of 25.7 % (95 % CI of 19.3-33.3) presented at the first visit with moderate/severe pain. Multiple logistic regression confirmed that age was the only factor to be significantly associated with moderate/severe pain and IOR classification was not able to provide a description of the pathology that was associated with a major pain score. Conclusion: from the early stages of multiple osteochondromas diagnosis

Indexed as

Multiple osteochondromasPainPrognostic factorsRare bone disease

Identifiers

PMID40206490
PMCPMC11978362

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.