ArticleCureus2025
Comparison of Trifecta Outcomes in Standard Versus Mini Percutaneous Nephrolithotomy for Renal Stone Management.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionUrolithiasis is a common urological condition, and percutaneous nephrolithotomy (PCNL) is a widely used treatment option for renal stones. The trifecta analysis, which includes the complete stone-free rate (SFR), absence of complications (Clavien-Dindo classification), and no need for auxiliary procedures, provides a standardized method for comparing outcomes. This study evaluates the trifecta outcomes of standard PCNL versus mini PCNL Methodology: This prospective cohort study was conducted at the Department of Urology, Institute of Kidney Diseases, Peshawar, from January 2022 to March 2024. A total of 180 consecutive patients who underwent PCNL were enrolled in the study. Using a lottery method, patients were randomly assigned to two equal groups (standard PCNL and mini PCNL). Both groups consisted of 90 patients each. Patients who required a change in the planned surgical procedure were replaced with new participants from the sample frame. A structured proforma was used to record preoperative, perioperative, and postoperative data for the trifecta analysis. Data were analyzed using IBM SPSS Statistics for Windows, Version 23.0 (Released 2015; IBM Corp., Armonk, NY, United States). Logistic regression was performed to assess predictive factors for the trifecta, and the odds ratio (OR), confidence interval (CI), and p-value were calculated.
resultsThe mean age in the standard PCNL group was 43.21 ± 3.51 years vs 44.03 ± 3.17 years in the mini PCNL group (p = 0.10). The mean stone size in the standard PCNL group was 30.62 ± 5.88 mm vs 30.28 ± 6.03 mm in the mini PCNL group (p = 0.70). The mean stone density in the standard PCNL group was 1366.25 ± 74.28 HU vs 1342.66 ± 107.34 HU in the mini PCNL group (p = 0.08). Stones were completely cleared in 84 (93.3%) patients in the standard PCNL group and 69 (76.7%) in the mini PCNL group (p = 0.02). Auxiliary procedures, including extracorporeal shock wave lithotripsy (ESWL), ureteroscopy (URS), and repeat double J (DJ) stenting, were required in four patients (4.4%) in the standard PCNL group compared to 20 patients (20%) in the mini PCNL group. Regarding complications, the standard PCNL group recorded complications in 16 patients (17.77%), including Grade 1 (six patients), Grade 2 (five patients), and Grade 3 (five patients), according to the Clavein-Dindo classification. In the mini PCNL group, six patients (6.66%) experienced postoperative complications, including Grade 1 (five patients) and Grade 2 (one patient) (p = 0.02). The overall trifecta success rate was 71.12% in the standard PCNL group vs 50.03% in the mini PCNL group.
conclusionThe trifecta analysis indicates that standard PCNL has a higher SFR, while mini PCNL is safer but requires more auxiliary procedures.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.