Evidence map›Paper›PMID 40210441›Full record

ArticleGenome research2025

Cohesin organizes 3D DNA contacts surrounding active enhancers in

Jun Kim, Haoyu Wang, Sevinç Ercan

Abstract read
In one paragraph

Article in Genome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  14. MIA-Jet: Multi-scale Identification Algorithm of Chromatin Jets.bioRxiv : the preprint server for biology · 2025
    Article
  15. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jun KimDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York 10003, USA.ORCID 0000-0001-9473-3093
Haoyu WangDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York 10003, USA.
Sevinç ErcanDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York 10003, USA sevinc@nyu.edu.ORCID 0000-0001-7297-1648

Funding

TRAINING PROGRAM IN DEVELOPMENTAL GENETICS.T32HD007520 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TREISMAN, JESSICA E · 1999 to 2023
$3.9M
Mechanisms of condensin-mediated gene regulation in C. elegansR35GM130311 · NIGMS · NEW YORK UNIVERSITY · PI Sevinc Ercan · 2019 to 2026
$3.3M
NICHD NIH HHS T32 HD007520NIGMS NIH HHS R35 GM130311
6 · The paper itself

Abstract

In mammals, cohesin and CTCF organize the 3D genome into topologically associating domains (TADs) to regulate communication between

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsChromosomal Proteins, Non-HistoneDNAEnhancer Elements, GeneticAnimalsCCCTC-Binding FactorCohesinsCaenorhabditis elegans ProteinsCCCTC-Binding FactorCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsDNA

Identifiers

PMID40210441
PMCPMC12047539

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.