SynthesisNature communications2025
Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.
Abstract readMeta-Analysis
In one paragraph
Synthesis in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Article
- Elucidating the susceptibility genes between insomnia and migraine by integrating genetic data and transcriptomes.The journal of headache and pain · 2026Article
- Admixture mapping identifies complex trait associations with local ancestry in themedRxiv : the preprint server for health sciences · 2025Article
- Nutrigenomics meets multi-omics: integrating genetic, metabolic, and microbiome data for personalized nutrition strategies.Genes & nutrition · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
94 authors.
Lauren E PettyVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Hung-Hsin ChenVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-1921-2797
Elizabeth G FrankelVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Wanying ZhuVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Carolina G DownieDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-6972-9981
Mariaelisa GraffDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-6380-1735
Phillip LinVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Priya SharmaDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Xinruo ZhangDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-5789-4592
Alyssa C ScartozziVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Rashedeh RoshaniVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua M LandmanVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0003-2431-6053
Michael BoehnkeDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-6442-7754
Donald W BowdenCenter for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
John C ChambersDepartment of Epidemiology and Biostatistics, Imperial College London, London, UK.
Anubha MahajanOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Mark I McCarthyOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Maggie C Y NgVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-4133-2007
Xueling SimSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.ORCID http://orcid.org/0000-0002-1233-7642
Cassandra N SpracklenDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Weihua ZhangDepartment of Epidemiology and Biostatistics, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-8279-3611
Michael PreussThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-5266-8465
Erwin P BottingerThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Girish N NadkarniThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-6319-4314
Ruth J F LoosThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-8532-5087
Yii-Der Ida ChenThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Jingyi TanThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Eli IppDivision of Endocrinology & Metabolism, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Pauline GenterDivision of Endocrinology & Metabolism, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Leslie S EmeryDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Tin LouieDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Tamar SoferDepartments of Medicine and Biostatistics, Harvard University, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8520-8860
Adrienne M StilpDepartment of Biostatistics, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3910-0776
Kent D TaylorThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Anny H XiangDepartment of Research & Evaluation, Division of Biostatistics Research, Kaiser Permanente of Southern California, Pasadena, CA, USA.
Thomas A BuchananDepartment of Medicine, Division of Endocrine, Keck School of Medicine of USC, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-7892-5132
Kathryn RollThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Chuan GaoMolecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-, Salem, NC, USA.ORCID http://orcid.org/0000-0002-4877-2072
Nicholette D PalmerDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID http://orcid.org/0000-0001-8883-2511
Jill M NorrisDepartment of Epidemiology, University of Colorado Denver, Aurora, CO, USA.ORCID http://orcid.org/0000-0001-8674-2598
Lynne E WagenknechtDivision of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Darryl NousomeDepartment of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Rohit VarmaSouthern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, CA, USA.
Roberta McKean-CowdinDepartment of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Xiuqing GuoThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0002-5264-5068
Yang HaiThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0002-9420-0614
Willa HsuehDepartment of Internal Medicine, Diabetes and Metabolism Research Center, Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-7321-4398
Kevin SandowThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Esteban J ParraDepartment of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.ORCID http://orcid.org/0000-0002-2057-8577
Miguel CruzUnidad de Investigación Médica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico.
Adan Valladares-SalgadoUnidad de Investigación Médica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico.
Niels Wacher-RodarteUnidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico.
Jerome I RotterThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Mark O GoodarziDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-6364-5103
Stephen S RichCenter for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.ORCID http://orcid.org/0000-0003-3872-7793
Alain BertoniDepartment of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Leslie J RaffelDepartment of Pediatrics, Division of Medical Genetics, UCI Irvine School of Medicine, Irvine, CA, USA.
Jerry L NadlerDepartment of Medicine and Pharmacology, New York Medical College, Valhalla, NY, USA.
Fouad R KandeelDepartments of Clinical Diabetes, Endocrinology & Metabolism and Translational Research and Cellular Therapeutics, City of Hope, Duarte, CA, USA.
Ravindranath DuggiralaHuman Genetics and STDOI, University of Texas Rio Grande Valley, Edinburg, TX, USA.
John BlangeroHuman Genetics and STDOI, University of Texas Rio Grande Valley, Edinburg, TX, USA.ORCID http://orcid.org/0000-0001-6250-5723
Donna M LehmanDepartment of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Ralph A DeFronzoDepartment of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Farook ThameemDepartment of Biochemistry, Faculty of Medicine, Health Science Center, Kuwait University, Safat, Kuwait.
Yujie WangDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-1087-2182
Sheila GahaganDivision of Academic General Pediatrics, Child Development and Community Health, University of California at San Diego, San Diego, CA, USA.
Estela BlancoCollege y Escuela de Salud Pública, Pontificia Universidad Católica de Chile, Santiago, Chile.
Raquel BurrowsDepartment of Public Health Nutrition, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
Alicia Huerta-ChagoyaConsejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Jose C FlorezDepartment of Medicine, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1730-9325
Teresa Tusie-LunaUnidad de Biología Molecular y Medicina Genómica, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Clicerio González-VillalpandoCentro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Pública, Mexico City, Mexico.
Lorena OrozcoInstituto Nacional de Medicina Genómica, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-5801-9180
Christopher A HaimanDepartment of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.
Craig L HanisHuman Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Rebecca RohdeDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Eric A WhitselDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-4843-3641
Alexander P ReinerDepartment of Epidemiology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-1427-4470
Charles KooperbergFred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7986-8560
Yun LiDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-9275-4189
Qing DuanDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Miryoung LeeDepartment of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA.
Paulina Correa-BurrowsDepartment of Public Health Nutrition, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.ORCID http://orcid.org/0000-0002-6177-1162
Susan K FriedDiabetes, Obesity Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-1101-9332
Kari E NorthDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-8903-0366
Joseph B McCormickDepartment of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA.ORCID http://orcid.org/0000-0002-5844-8102
Susan P Fisher-HochDepartment of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA.
Eric R GamazonVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0003-4204-8734
Andrew P MorrisCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-6805-6014
Josep M MercaderDepartment of Medicine, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8494-3660
Heather M HighlandDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-3583-8239
Jennifer E BelowVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. jennifer.e.below@vanderbilt.edu.ORCID http://orcid.org/0000-0002-1346-1872
DIAMANTE Hispanic/Latino Consortium
Global Hispanic Lipids Consortium
Funding
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3MIdentifying Genes for Type 2 Diabetes: FUSIONU01DK062370 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOEHNKE, MICHAEL L, SCOTT, LAURA J. · 2009 to 2021
$11.6MCHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5MIdentifying Genes for Type 2 Diabetes:FUSIONR01DK062370 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOEHNKE, MICHAEL L, SCOTT, LAURA J. · 2003 to 2025
$6.7MHispanic Latino Lipid ConsortiumR01HL142302 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jennifer Below, JOSEPH MCCORMICK · 2018 to 2026
$5.8MDevelopment of Polygenic Risk Scores for Diabetes and Complications across the Life-Span in Populations of Multiple AncestriesU01HG011723 · NHGRI · BROAD INSTITUTE, INC. · PI Alisa Knodle Manning, Josep Maria Mercader · 2021 to 2026
$5.7MSOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0MGenetic Epidemiology of Causal Variants across the Life Course Phase II (CALiCo IU01HG007416 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NORTH, KARI E. · 2013 to 2017
$3.9MMechanisms regulating functional heterogeneity of subcutaneous adipose tissues in womenR01DK121547 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FRIED, SUSAN K · 2019 to 2023
$3.5MMulti-omics for obesity-associated liver disease in a high-risk population cohortU01CA288325 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Jennifer Below, JOSEPH MCCORMICK · 2023 to 2026
$3.3MStudy of coding variants in human obesity and their functional characterization using human iPSC-derived cellular modelsR01DK110113 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LOOS, RUTH JF · 2016 to 2020
$2.8MSearch for obesity-associated genes with protective effects on metabolic healthR01DK107786 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LOOS, RUTH JF · 2017 to 2020
$2.3MNCI NIH HHS U01 CA288325NEI NIH HHS R01 EY036258NHGRI NIH HHS R56 HG010297NHGRI NIH HHS U01 HG007416NHGRI NIH HHS U01 HG011723NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL142302NIBIB NIH HHS R01 EB015611NIDCD NIH HHS F31 DC022482NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK062370NIDDK NIH HHS R01 DK101855NIDDK NIH HHS R01 DK107786NIDDK NIH HHS R01 DK110113NIDDK NIH HHS R01 DK121547NIDDK NIH HHS R01 DK139598NIDDK NIH HHS R56 DK062370NIDDK NIH HHS U01 DK062370U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL142302
Abstract
Here, we present a multi-omics study of type 2 diabetes and quantitative blood lipid and lipoprotein traits conducted to date in Hispanic/Latino populations (n
Indexed as
Diabetes Mellitus, Type 2Hispanic or LatinoCholesterol, HDLFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansLipidsMaleMembrane ProteinsMendelian Randomization AnalysisMultiomicsPolymorphism, Single NucleotideProteomicsQuantitative Trait LociTriglyceridesCholesterol, HDLLipidsMembrane ProteinsTriglycerides
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.