ReviewLasers in medical science2025
Recent advances in laser interstitial thermal therapy in the treatment of brain metastases and radiation necrosis.
Review in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Laser Interstitial Thermal Therapy for High-Grade Gliomas: Current Evidence, Clinical Applications and Emerging Role of Artificial Intelligence.Journal of clinical medicine · 2026Review
- Advances in the prevention and treatment of radiation-induced brain necrosis: a narrative review.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis manuscript reviews advancements in Laser Interstitial Thermal Therapy (LITT) for treating brain metastases and radiation necrosis, emphasizing its minimally invasive nature and precision in targeting deep-seated or eloquent area lesions. It analyzes studies from 2011 to 2024 to evaluate LITT's efficacy, safety, and complications while highlighting the need for standardized clinical endpoints. Despite its potential, LITT remains a secondary treatment due to limited high-level evidence, requiring further research and multidisciplinary collaboration.
methodsA systematic PubMed search identified 2,004 articles on LITT for brain metastases and radiation necrosis. Filtering for studies from 2011 to 2024 resulted in 60 selected articles: 4 clinical trials, 22 observational studies, 3 case reports, 2 case series, and the rest review articles. Relevant data were extracted, analyzed, and compiled for this review.
resultsLITT is primarily used for lesions unsuitable for open craniotomy, such as deep-seated or eloquent-area tumors. Literature supports its increasing neuro-oncological applications, particularly in brain metastases, gliomas, meningiomas, and radiation necrosis.
conclusionThe evolving landscape of brain metastasis treatment underscores the importance of a multidisciplinary approach incorporating standardized reporting, advanced imaging, and molecular diagnostics. Further innovation and collaboration are needed to optimize LITT's role in neuro-oncology and address treatment challenges in the era of personalized medicine.
Indexed as
Identifiers
40210749What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.