ArticleBMC pregnancy and childbirth2025
The value of fetal growth trajectory during pregnancy in predicting small for gestational age neonates at term.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Genetic and maternal environmental contributions to estimated fetal weight at 20 weeks gestation compared with birthweight.medRxiv : the preprint server for health sciences · 2026Article
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8 authors.
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Abstract
backgroundThe predictive value of trajectory identified by group-based trajectory modeling (GBTM) has been discussed but its value in predicting small for gestational age (SGA) neonates is still unclear. This study aims to describe the trajectory of fetal growth of estimated fetal weight (EFW) during pregnancy and compare its performance to growth velocity of EFW and EFW z-scores at each scan in predicting SGA neonates at term.
methodsThe growth trajectory for EFW obtained from ultrasound scan at around 23-24, 31-32, 37-39 weeks of gestation of 1699 women from Shenzhen Birth Cohort Study was identified using GBTM. The area under receiver operating characteristics curve (AUC), Brier scores and Decision curve analysis (DCA) was used to evaluate the discrimination, calibration performance and clinical usefulness of EFW growth trajectory, EFW growth velocity between each stage and EFW z-scores at each scan.
resultsFour trajectory groups of EFW which described as "very low-stable", "low-stable", "average-stable", "rising-falling" were identified. The growth trajectory performed better in discrimination and calibration than growth velocity, with AUC of 0.76 (95%CI: 0.73-0.80) and Brier score of 0.067 in predicting SGA neonates at term. When compared to the EFW z-scores, growth trajectory performed better than EFW z-scores of 23-24 weeks (AUC = 0.72, 95%CI: 0.68-0.76, Brier score = 0.073), but not as well as EFW z-scores of 37-39 weeks of gestation (AUC = 0.88, 95%CI: 0.86-0.91, Brier score = 0.060).
conclusionsEFW z-scores of 37-39 weeks of gestation outperformed in predicting SGA neonates at term than growth trajectory and velocity. Growth trajectory has better potential for serial ultrasound examinations to describe the process of fetal growth and to predict SGA neonates at term than fetal growth velocity.
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