Evidence map›Paper›PMID 40211138›Full record

ArticleBMC plant biology2025

Genome-wide identification and analysis of Rop GTPase family members reveal their potential functions in biotic stress in potato (Solanum tuberosum L.).

Zhida Liu, Guochao Xuanyuan, Shuqing Yang, Miru Du, Xiaoluo Zhang, Tingting Bao, Zhiwei Zhang, Wenbing Zhang, Jun Zhao

Abstract read
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In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Zhida Liu *College of Horticulture and Plant Protection, Inner Mongolia Agricultural University, Hohhot, 010019, China.
Guochao Xuanyuan *The Modern Agriculture and Husbandry Research Center, Inner Mongolia Open University, Hohhot, 010010, China.
Shuqing YangCollege of Agriculture, Tarim University, Alaer, 843300, China.
Miru DuInner Mongolia Potato Engineering and Technology Research Centre, Inner Mongolia University, Hohhot, 010021, China.
Xiaoluo ZhangInner Mongolia Agricultural and Animal Husbandry Technology Extension Center, Hohhot, 010031, China.
Tingting BaoHohhot Garden Construction Service Center, Hohhot, 010030, China.
Zhiwei ZhangCollege of Horticulture and Plant Protection, Inner Mongolia Agricultural University, Hohhot, 010019, China.
Wenbing ZhangCollege of Horticulture and Plant Protection, Inner Mongolia Agricultural University, Hohhot, 010019, China. zhangwenbing@imau.edu.cn.
Jun ZhaoCollege of Horticulture and Plant Protection, Inner Mongolia Agricultural University, Hohhot, 010019, China. zhaojun@imau.edu.cn.

Funding

Key Program of Science and Research in Universities of Inner Mongolia Autonomous Region NJZZ23064Key Projects of Natural Science Foundation of Inner Mongolia Autonomous Region 2022ZD10Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region NJYT23111Research Start-up Funds for High-level Researchers in Inner Mongolia Agricultural University NDYB2019-02
6 · The paper itself

Abstract

backgroundRop (RHO of plants) proteins are the plant-specific subfamily of RHO small GTP-binding proteins and act as a molecular switch to converge on a wide range of upstream signals and elicit downstream signaling cascades involving in modulating developmental processes and managing environmental stress. Although the function of Rops has been well studied in many plant species, the research conducting on Rops in potato is limited.

resultsIn this work, a total of 11 Rop members were identified in the potato (Solanum tuberosum) genome. A comprehensive analysis encompassing their phylogenetic relationships, chromosomal locations, collinearity, conserved motifs, gene structures, cis-regulatory elements, tissue-specific expression profiles, and responses to biotic stress were undertaken. Phylogenetic and collinearity analyses suggested that 11 StRops were categorized into four groups, and five StRop genes (StRop6, StRop7, StRop8, StRop9 and StRop10) were incorporated in segmental duplication events. Synteny analysis indicated that five and eight StRop genes were orthologous to Arabidopsis (Arabidopsis thaliana) and tomato (Solanum lycopersicum), respectively. Tissue-specific expression analysis confirmed that StRops were widely expressed in various potato tissues, with variety-specific expression, implicating their multiple roles in growth and development in potato. The cis-regulatory elements related to stress response and hormone response were found in the promoters of StRop genes. Most StRops, including StRop2, StRop3, StRop8, StRop9, StRop10 and StRop11, were shown to be significantly differentially expressed in three different cultivars after infection with various pathogens (Phytophthora infestans, Fusarium oxysporum and Verticillium dahliae). Knock-down each of StRop3, StRop7 and StRop8 by virus induced gene silencing (VIGS) resulted in increased susceptibility of potato to pathogens P. infestans and V. dahliae, and transient silencing of StRop6 led to enhanced potato root colonization by V. dahliae, indicating their distinct roles in response to different pathogen challenges.

conclusionsThe results unveil the structural characteristics of StRop genes, and provide the basic knowledge for further elucidating the gene functions of individual members in response to biotic stress.

Indexed as

Plant ProteinsSolanum tuberosumFusariumGene Expression Regulation, PlantGenome, PlantGenome-Wide Association StudyPhylogenyPlant DiseasesStress, PhysiologicalPlant ProteinsGene expressionPotato biotic stressRopSmall GTPaseVirus-induced gene silencing (VIGS)

Identifiers

PMID40211138
PMCPMC11983853

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.