Evidence map›Paper›PMID 40213658›Full record

ArticleTheranostics2025

Augmented expression of superoxide dismutase 2 mitigates progression and rupture of experimental abdominal aortic aneurysm.

Huimin Yan, Ying Hu, Yang Lyu, Antonina Akk, Angela C Hirbe, Samuel A Wickline, Hua Pan, Elisha D O Roberson, Christine T N Pham

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. mRNA medicine for cardiovascular disease.Nature cardiovascular research · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Huimin YanThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Ying HuThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Yang LyuThe Department of Medicine, Division of Oncology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Antonina AkkThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Angela C HirbeThe Department of Medicine, Division of Oncology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Samuel A WicklineThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Hua PanThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Elisha D O RobersonThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Christine T N PhamThe Department of Medicine, Division of Rheumatology, Washington University School of Medicine, Saint Louis, Missouri, USA.

Funding

Washington University Rheumatic DiseasesResearch Resource-based CenterP30AR073752 · NIAMS · WASHINGTON UNIVERSITY · PI Deborah J Lenschow, Christine T. Pham · 2018 to 2026
$7.6M
Prediction and Treatment for Cancer Immunotherapy Induced MyocarditisR21HL154009 · NHLBI · WASHINGTON UNIVERSITY · PI PAN, HUA · 2021 to 2022
$423k
BLRD VA I01 BX005075NHLBI NIH HHS R21 HL154009NIAMS NIH HHS P30 AR073752
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aortic Aneurysm, AbdominalAortic RuptureSuperoxide DismutaseAnimalsAntioxidantsApoptosisDisease Models, AnimalDisease ProgressionHumansMaleMiceMice, Inbred C57BLOxidative StressReactive Oxygen SpeciesSuperoxide Dismutase 2AntioxidantsReactive Oxygen SpeciesSuperoxide DismutaseSuperoxide Dismutase 2abdominal aortic aneurysmnanomedicineoxidative stressproteomicsSOD2 mRNA

Identifiers

PMID40213658
PMCPMC11980667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.