ReviewCureus2025
A Comprehensive Review on the Influence of Menstrual Cycle and Pregnancy on Epileptic Seizures.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Menopause and neurological disorders: a roadmap for research.Nature reviews. Neurology · 2026Review
- Anti-seizure potential of J4, an equilibrative nucleoside transporter 1 inhibitor, in a mouse model of tuberous sclerosis complex in response to pentylenetetrazol.Cell & bioscience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This narrative review aims to assess the influence of hormonal balance during the menstrual cycle and pregnancy on the severity of epileptic seizures. Hormonal fluctuations, particularly in estrogen and progesterone levels, significantly influence neuronal excitability and seizure thresholds, with estrogen generally enhancing excitatory activity and progesterone providing a stabilizing effect. These hormonal variations are particularly evident in conditions like catamenial epilepsy, where seizure frequency corresponds to specific phases of the menstrual cycle. Pregnancy adds further complexity, as shifts in hormonal dominance can lead to variable effects on seizure patterns. Understanding these interactions is crucial for developing tailored management strategies to improve outcomes for women with epilepsy during their reproductive years. This review consolidates existing knowledge and highlights areas where further research is needed to address clinical challenges and optimize care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.