Evidence map›Paper›PMID 40214433›Full record

ArticleCells2025

Impact of a Heterozygous C1R

Chengjuan Qu, Cecilia Koskinen Holm

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chengjuan QuDepartment of Odontology, Umeå University, 90185 Umeå, Sweden.ORCID 0000-0002-1710-7715
Cecilia Koskinen HolmDepartment of Odontology, Umeå University, 90185 Umeå, Sweden.

Funding

Knut and Alice Wallenberg Foundation RV-812171TUA-research grant from region Västerbotten RV-937484
6 · The paper itself

Abstract

Periodontal Ehlers-Danlos syndrome arising from heterozygous pathogenic mutation in

Indexed as

CollagenFibroblastsGingivaInflammationMutationHeterozygoteHSP47 Heat-Shock ProteinsHumansMatrix Metalloproteinase 1CollagenHSP47 Heat-Shock ProteinsMatrix Metalloproteinase 1SERPINH1 protein, humancollagen metabolismcomplement component 1r/1s (C1r/C1s)heterozygous C1RR301P/WT-mutated human TERT-immortalized gingival fibroblasts (mhGFBs)periodontal Ehlers–Danlos syndrome

Identifiers

PMID40214433
PMCPMC11987961

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.