Evidence map›Paper›PMID 40216787›Full record

ArticleNature communications2025

Highly dynamic and sensitive NEMOer calcium indicators for imaging ER calcium signals in excitable cells.

Wenjia Gu, Jia-Hui Chen, Yiyin Zhang, Zhirong Wang, Jia Li, Sijia Wang, Hanhan Zhang, Amin Jiang, Ziyi Zhong, Jiaxuan Zhang and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Calcium signaling in crops.The New phytologist · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Wenjia Gu *Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Jia-Hui Chen *Department of Anatomy, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.
Yiyin Zhang *State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, China.
Zhirong Wang *Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0002-6787-9756
Jia Li *Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0000-0003-1274-3867
Sijia WangInstitute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0009-0003-2340-5123
Hanhan ZhangBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Amin JiangNational Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Ziyi ZhongBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Jiaxuan ZhangBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Ze XuState Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, China.
Panpan LiuBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Chao XiBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Tingting HouState Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, China.
Donald L GillDepartment of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Dong LiNational Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-6787-5125
Yu MuInstitute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. my@ion.ac.cn.ORCID http://orcid.org/0000-0001-9297-4854
Shi-Qiang WangState Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, China. wsq@pku.edu.cn.ORCID http://orcid.org/0000-0001-7784-4461
Ai-Hui TangAnhui Province Key Laboratory of Biomedical Imaging and Intelligent Processing, Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China. tangah@ustc.edu.cn.ORCID http://orcid.org/0000-0003-3715-6714
Youjun WangBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China. wyoujun@bnu.edu.cn.ORCID http://orcid.org/0000-0003-0961-1716

Funding

Understanding Store-Operated Calcium Signal TransductionR35GM131916 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GILL, DONALD L · 2019 to 2023
$2.9M
Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2019YFA0802104National Natural Science Foundation of China (National Science Foundation of China) 32250003, 32230048National Natural Science Foundation of China (National Science Foundation of China) 92254301, W2411015NIGMS NIH HHS R35 GM131916
6 · The paper itself

Abstract

The Endoplasmic/sarcoplasmic reticulum (ER/SR) is central to calcium (Ca

Indexed as

CalciumCalcium SignalingAnimalsCells, CulturedEndoplasmic ReticulumGenes, ReporterHomeostasisHumansMuscle, SkeletalZebrafishCalcium

Identifiers

PMID40216787
PMCPMC11992197

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.