Evidence map›Paper›PMID 40217604›Full record

ReviewJournal of clinical medicine2025

Coinfections in Tuberculosis in Low- and Middle-Income Countries: Epidemiology, Clinical Implications, Diagnostic Challenges, and Management Strategies-A Narrative Review.

Ramona Cioboata, Mara Amalia Balteanu, Andrei Osman, Silviu Gabriel Vlasceanu, Ovidiu Mircea Zlatian, Denisa Maria Mitroi, Oana Maria Catana, Adriana Socaci, Eugen-Nicolae Tieranu

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  16. Molecular signaling in coinfection: howFrontiers in immunology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ramona CioboataPneumology Department, University of Medicine and Pharmacy, 200349 Craiova, Romania.ORCID 0009-0006-6335-1627
Mara Amalia BalteanuDepartment of Pulmonology, Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania.ORCID 0009-0004-8409-5904
Andrei OsmanDepartment of Anatomy and Embryology, University of Medicine and Pharmacy, 200349 Craiova, Romania.ORCID 0000-0001-6967-3789
Silviu Gabriel VlasceanuDepartment of Physiology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0007-3856-7917
Ovidiu Mircea ZlatianDepartment of Microbiology, University of Medicine and Pharmacy, 200349 Craiova, Romania.ORCID 0000-0003-3510-3838
Denisa Maria MitroiDoctoral School, University of Medicine and Pharmacy, 200349 Craiova, Romania.
Oana Maria CatanaDoctoral School, University of Medicine and Pharmacy, 200349 Craiova, Romania.ORCID 0009-0000-9976-2256
Adriana SocaciDepartment of Biology and Life Science, Vasile Goldis University Arad, 310025 Arad, Romania.ORCID 0000-0001-6006-8443
Eugen-Nicolae TieranuDepartment of Internal Medicine-Cardiology, University of Medicine and Pharmacy, 200349 Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) continues to be a major public health challenge in low- and middle-income countries (LMICs), where high burdens of coinfections exacerbate the disease's impact. In 2023, an estimated 8.2 million people were newly diagnosed with tuberculosis worldwide, reflecting an increase from 7.5 million in 2022 and 7.1 million in 2019. In LMICs, limited access to healthcare, inadequate nutrition, and poor living conditions contribute to higher coinfection rates among TB patients, leading to delayed diagnosis and treatment, which in turn exacerbates disease severity and facilitates transmission. This narrative review synthesizes the epidemiology, clinical implications, diagnostic challenges, and management strategies related to TB coinfections with viral pathogens including HIV, SARS-CoV-2, and influenza, bacteria such as

Indexed as

coinfectionsCOVID-19HIVlow- and middle-income countriestuberculosis

Identifiers

PMID40217604
PMCPMC11989680

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.