ReviewAnimals : an open access journal from MDPI2025
Blood Biochemical Biomarkers in Fish Toxicology-A Review.
Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Hematological and biochemical alterations in rainbow trout Oncorhynchus mykiss during a natural Aeromonas sp. outbreak in high-altitude Ladakh, trans-Himalayas.Archives of microbiology · 2026Article
- Dietary naringenin modulates antioxidant status and hepatic lipid deposition in marine medaka (Oryzias dancena) fed a high-fat diet.Fish physiology and biochemistry · 2026Article
- The Inclusion of Supercritical Fluid Extract ofAntioxidants (Basel, Switzerland) · 2026Article
- Full-Fat Black Soldier Fly Larvae Meal in Diets for Pacu,Animals : an open access journal from MDPI · 2026Article
- Impacts of Cinnamomum tamala leaf extract on growth, skin mucosal and serum immunity, antioxidant activity, and expression of cytokine genes in Cyprinus carpio fingerlings.Fish physiology and biochemistry · 2026Article
- Analysis of hepatic and serum responses to acute cold stress in juvenile yellowfin tuna Thunnus albacares (Bonnaterre 1788).Journal of fish biology · 2026Article
- Dietary supplementation with gac (<em>Momordica cochinchinensis</em>) aril powder and oil enhances coloration, hemato-biochemical parameters, and immunity-related gene expression in ornamental goldfish.Veterinary world · 2026Article
- Effects of Seawater Acclimation on Serum Biochemistry, Hormones, Splenic Immunity, Hepatic Lipid Metabolism, and Intestinal Microbiota in the FAnimals : an open access journal from MDPI · 2026Article
- Dietary Methionine Affects Lipid Metabolism and Ferroptosis-Related Responses to Modulate Oxidative Stress Induced by High-Lipid-Diet in Golden Pompano (Antioxidants (Basel, Switzerland) · 2026Article
- Article
- Effects of Hydrogen-Rich Water on Antioxidant Capacity, Immune Response, and Gut Microbiota in Juvenile Snakehead (Animals : an open access journal from MDPI · 2026Article
- Chronic toxicological impacts of tire rubber nanoparticles on hematobiochemical, oxidative stress, and immunological responses in Nile tilapia (Oreochromis niloticus).Fish physiology and biochemistry · 2026Article
- Dietary cauliflower (Brassica oleracea var. botrytis) mitigates benzo[a]pyrene-induced oxidative stress, immune dysfunction, and tissue damage in Nile tilapia.Scientific reports · 2026Article
- Dietary Yellow Bells (Animals : an open access journal from MDPI · 2026Article
- Acute effect of tetracycline on systemic stress markers and organ histopathology in juvenile Nile tilapia,Toxicology reports · 2026Article
- Effects of a nicosulfuron-based herbicide on common carpJournal of veterinary research · 2026Article
- Effects of Dietary Host-DerivedAnimals : an open access journal from MDPI · 2026Article
- Liver Transcriptome Analysis Revealed the Physiological Response Mechanism of Red-Spotted Grouper (Animals : an open access journal from MDPI · 2026Article
- Dietary Probiotics Modulate Oxidative Stress, Metabolic Status, and Immune-Related Gene Expression in Nile Tilapia (Veterinary sciences · 2026Article
- Evaluating poultry by-product meal, tomato pomace, and azolla with or without Natuzyme supplementation as sustainable alternatives to fish meal for Nile tilapia (Oreochromis niloticus).Tropical animal health and production · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood-based biochemical assays are used as predictive and diagnostic methods to evaluate fish welfare in aquaculture and research. The variations of blood biochemical parameters in fish are commonly used as biomarkers of exposure to toxic agents. Blood biochemical parameters can help identify the magnitude of toxicity and the mechanisms by which particular toxic agents act on the organisms. Some parameters typically measured in the blood can also be evaluated in the whole body in the early developmental stages of fish (embryos and larvae) that are often used in toxicological studies. This review assessed the usefulness of various blood biochemical indices as toxicity biomarkers. Analysis of multiple studies showed that toxicity-induced changes in most blood biochemical parameters in fish often depend on toxic agent concentration and exposure duration. Also, various parameters manifest different sensitivity to intoxication, and diverse directions of changes may occur. Among biochemical parameters, some are biomarkers of general physiological stress, while others indicate dysfunctions of particular organs. Moreover, hormonal endpoints seem to be sensitive but nonspecific biomarkers of intoxication in fish.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.