Evidence map›Paper›PMID 40218880›Full record

ReviewNutrients2025

Effects of B Vitamins on Homocysteine Lowering and Thrombotic Risk Reduction-A Review of Randomized Controlled Trials Published Since January 1996.

Mengyan Li, Ruodi Ren, Kunkun Wang, Shan Wang, Allison Chow, Andrew K Yang, Yun Lu, Christopher Leo

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengyan LiBrigham and Women's Hospital, Boston, MA 02115, USA.
Ruodi RenCollege of Pharmacy, University of Minnesota, Minneapolis, MN 55415, USA.
Kunkun WangFairbanks Memorial Hospital, 340 Cowles Street, Fairbanks, AK 99701, USA.ORCID 0000-0002-5916-0311
Shan WangNYU Langone Hospital-Long Island, Mineola, NY 11501, USA.ORCID 0000-0002-2222-6356
Allison ChowCollege of Arts and Science, New York University, New York, NY 10012, USA.
Andrew K YangDartmouth College, Hanover, NH 03755, USA.
Yun LuCollege of Pharmacy, University of Minnesota, Minneapolis, MN 55415, USA.ORCID 0000-0003-4769-9712
Christopher LeoDuke Raleigh Hospital, a Campus of Duke University Hospital, School of Medicine, Duke University, Durham, NC 27708, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homocysteine is an amino acid derived from methionine which is metabolized via vitamin B

Indexed as

Dietary SupplementsHomocysteineThrombosisVitamin B ComplexHumansHyperhomocysteinemiaRandomized Controlled Trials as TopicRisk FactorsVitamin B 12Vitamin B 6HomocysteineVitamin B 12Vitamin B 6Vitamin B Complexcobalaminfolatefolic acidhomocysteinepyridoxinerandomized controlled trialsthromboembolic riskthrombosisvitamin B

Identifiers

PMID40218880
PMCPMC11990291

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.