Evidence mapPaperPMID 40218949Full record

Trial reportNutrients2025

A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of

Sung-Bum Lee, Byungwook Yoo, Chaemin Baeg, Jiae Yun, Dong-Wook Ryu, Gyungcheon Kim, Seongok Kim, Hakdong Shin, Ju Hee Lee

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sung-Bum LeeDepartment of Family Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 22972, Republic of Korea.
Byungwook YooDepartment of Family Medicine, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea.ORCID 0000-0002-8753-9660
Chaemin BaegGlobal Medical Research Center, Seoul 06526, Republic of Korea.
Jiae YunGwanggyo R&D Center, Medytox Inc., Suwon 16506, Republic of Korea.ORCID 0009-0007-5282-7842
Dong-Wook RyuGwanggyo R&D Center, Medytox Inc., Suwon 16506, Republic of Korea.
Gyungcheon KimDepartment of Food Science & Biotechnology, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.
Seongok KimDepartment of Food Science & Biotechnology, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.ORCID 0009-0007-7313-5386
Hakdong ShinDepartment of Food Science & Biotechnology, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.ORCID 0000-0001-7615-9809
Ju Hee LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate the efficacy and safety of probiotics for body fat reduction in obese individuals.

methodsA total of 106 participants with a body mass index between 25 and 30 kg/m

resultsAfter 12 weeks of follow-up period, the body fat mass decreased significantly, from 30.0 ± 4.4 to 28.3 ± 4.1 kg in the experimental group (

conclusionsLMT1-48 also positively influenced the microbial taxa linked to obesity analyzed by gut microbiome sequencing. LMT1-48 is a safe and collaborative agent to reduce obesity.

Indexed as

Adipose TissueLactiplantibacillus plantarumObesityProbioticsAbsorptiometry, PhotonAdultBody CompositionBody Mass IndexDouble-Blind MethodFecesFemaleGastrointestinal MicrobiomeHumansMaleMiddle AgedTreatment Outcomebody fat lossLactobacillus plantarumobesityprobiotics

Identifiers

PMID40218949
PMCPMC11990557

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.