Evidence map›Paper›PMID 40220258›Full record

ArticleOncology and therapy2025

Clinical and Dosimetric Predictors of Early Onset Postradiation Hypothyroidism in Patients with Head and Neck Malignancies: A Logistic Regression Analysis.

Ahmad Ameri, Zohreh Azma, Khashayar Fattah, Fereshteh Talebi, Pooya Ameri, Nazanin Rahnama, Mansour Lesan, Sanaz Poshtmahi, Farahnaz Rahimi, Marjan Mirsalehi and 1 more

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Article in Oncology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmad AmeriDepartment of Clinical Oncology, Imam Hossein Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zohreh AzmaErfan Radiation Oncology Center, Erfan Niayesh Hospital, Tehran, Iran.
Khashayar FattahDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Fereshteh TalebiDepartment of Clinical Oncology, Imam Hossein Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pooya AmeriSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nazanin RahnamaDepartment of Radiation Oncology, University Hospital of Zürich, Zurich, Switzerland.
Mansour LesanDepartment of Clinical Oncology, Imam Hossein Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sanaz PoshtmahiInstitute for Applied Physics, Eberhard Karls University Tübingen, Tubingen, Germany.
Farahnaz RahimiErfan Radiation Oncology Center, Erfan Niayesh Hospital, Tehran, Iran.
Marjan MirsalehiENT and Head and Neck Research Center and Department, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Farzad Taghizadeh-HesaryENT and Head and Neck Research Center and Department, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran. farzadth89@gmail.com.ORCID http://orcid.org/0000-0002-6195-2203

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypothyroidism commonly occurs as a side effect following radiotherapy for head and neck malignancies, yet limited information exists to predict the risk of postradiation hypothyroidism. This study aims to investigate the clinical and dosimetric factors that may predict early onset postradiation hypothyroidism (EO-PRH).

methodsA retrospective study was conducted on patients with head and neck cancer treated between 2018 and 2021, with a minimum follow-up duration of 12 months. The thyroid gland was contoured on computed tomography (CT) scans, and dose-volume histograms were analyzed, incorporating thyroid volume and V

resultsAmong the 84 eligible patients, 17 (20.2%) developed hypothyroidism within 1 year. The percentage of thyroid volume receiving 30 Gy (V

conclusionsV

Indexed as

DosimetryHead and neck cancerHypothyroidismRadiotherapy

Identifiers

PMID40220258
PMCPMC12129879

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.