Evidence map›Paper›PMID 40222723›Full record

SynthesisAdvances in nutrition (Bethesda, Md.)2025

Prognostic and Associative Significance of Malnutrition in Sarcopenia: A Systematic Review and Meta-Analysis.

Konstantinos Prokopidis, Giuseppe Dario Testa, Christoforos D Giannaki, Pinelopi Stavrinou, Eirini Kelaiditi, Emiel O Hoogendijk, Nicola Veronese

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Advances in nutrition (Bethesda, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Observational
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. NutrigramFrontiers in nutrition · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos ProkopidisDepartment of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom. Electronic address: k.prokopidis@liverpool.ac.uk.
Giuseppe Dario TestaDepartment of Geriatric and Intensive Care Medicine, Careggi Hospital, University of Florence, Florence, Italy.
Christoforos D GiannakiDepartment of Life Sciences, School of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Pinelopi StavrinouDepartment of Life Sciences, School of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Eirini KelaiditiFaculty of Sport, Allied Health and Performance Science, St Mary's University, Twickenham, United Kingdom.
Emiel O HoogendijkDepartment of General Practice, Amsterdam Public Health research institute, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology & Data Science, Amsterdam Public Health research institute, VU University Medical Center, Amsterdam, The Netherlands.
Nicola VeroneseDepartment of Health Promotion, Mother Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malnutrition is a common phenomenon, particularly in those at an increased risk of muscle mass and function losses. In this systematic review and meta-analysis, we aimed to explore the association of malnutrition with sarcopenia in middle-aged and older adults and the prognostic association of malnutrition and sarcopenia compared with sarcopenia alone on all-cause mortality. PubMed, Scopus, Web of Science, and Cochrane Library were searched from inception until January 2024. A meta-analysis using a random-effect model was employed, utilizing the Mini Nutritional Assessment malnutrition tool as a continuous and categorical variable. The study protocol was registered in the International Prospective Register of Systematic Reviews (CRD42024501521). Malnutrition was significantly associated with a greater risk of sarcopenia [continuous: k = 12, odds ratio (OR): 1.38, 95% confidence interval (CI): 1.18, 1.61, I

Indexed as

MalnutritionSarcopeniaAgedFemaleHumansMaleMiddle AgedNutrition AssessmentPrognosisRisk Factorsageingmalnutritionmini nutritional assessmentmortalitysarcopenia

Identifiers

PMID40222723
PMCPMC12099873

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.