Evidence map›Paper›PMID 40224248›Full record

ArticleVeterinary medicine international2025

Safety and Immunogenicity of Recombinant Adeno-Associated Virus-Vectored African Swine Fever Virus Antigens.

Antonina Galeeva, Marina Efimova, Gennadiy Frolov, Nail Khammadov, Almaz Hisamutdinov, Lenar Garipov, Danil Mingaleev, Rustam Ravilov

Abstract read
In one paragraph

Article in Veterinary medicine international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonina GaleevaInterdepartmental Laboratory of Immunology and Biotechnology, Kazan State Academy of Veterinary Medicine Named After N.E. Bauman, Kazan, Russia.ORCID https://orcid.org/0000-0003-2650-6459
Marina EfimovaLaboratory of Viral Antropozoonoses, Federal Center for Toxicological, Radiation and Biological Safety, Kazan, Russia.ORCID https://orcid.org/0000-0001-8786-1310
Gennadiy FrolovDepartment of Epizootology and Parasitology, Kazan State Academy of Veterinary Medicine Named After N.E. Bauman, Kazan, Russia.ORCID https://orcid.org/0000-0003-0042-5693
Nail KhammadovInterdepartmental Laboratory of Immunology and Biotechnology, Kazan State Academy of Veterinary Medicine Named After N.E. Bauman, Kazan, Russia.ORCID https://orcid.org/0000-0001-5669-1486
Almaz HisamutdinovMinistry of Agriculture and Food of Republic of Tatarstan, Kazan, Russia.
Lenar GaripovMinistry of Agriculture and Food of Republic of Tatarstan, Kazan, Russia.
Danil MingaleevDepartment of Epizootology and Parasitology, Kazan State Academy of Veterinary Medicine Named After N.E. Bauman, Kazan, Russia.ORCID https://orcid.org/0000-0001-7217-4083
Rustam RavilovDepartment of Epizootology and Parasitology, Kazan State Academy of Veterinary Medicine Named After N.E. Bauman, Kazan, Russia.ORCID https://orcid.org/0000-0001-7210-7470

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the significant global economic damage caused by African swine fever (ASF) and ongoing developments in the field of specific prevention tools development, safe and effective vaccines are still missing. A critical factor hindering the development of ASF vaccines is the lack of sufficient data on the pathogenesis of the virus, as well as a deep understanding of the virus' evasion strategies from the innate immune system. Of particular interest in the design of candidate vaccines are viral vectors, especially-adeno-associated virus (AAV), which is widely used in gene therapy and is capable of long-term transgene expression in vivo. This study assessed the safety and immunogenicity of recombinant AAV serotype 2 (rAAV2), into the genome of which the ASF virus

Identifiers

PMID40224248
PMCPMC11986952

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.