Evidence map›Paper›PMID 40224261›Full record

ArticleHeart rhythm O22025

Catheter ablation for atrial fibrillation and risk of neurologic disease.

Mohammed Al-Sadawi, Nithi Tokavanich, Jasneet Devgun, Michael Ghannam, Rakesh Latchamsetty, Krit Jongsarangsin, Hakan Oral

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammed Al-SadawiClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.
Nithi TokavanichClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.
Jasneet DevgunClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.
Michael GhannamClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.
Rakesh LatchamsettyClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.
Krit JongsarangsinClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.
Hakan OralClinical Cardiac Electrophysiology Department, University of Michigan Hospital, Ann Arbor, Michigan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Catheter ablation (CA) of atrial fibrillation (AF) has been proven to benefit patients with symptomatic AF and heart failure. However, the data on neurological outcomes including cerebrovascular accidents (CVA) and dementia remain controversial. Objective: We aimed to determine the effect of CA on neurological events during long-term follow-up. Methods: We performed a systematic review and meta-analysis of patients with AF who underwent CA of AF. The MEDLINE, EMBASE, and Web of Science databases were comprehensively searched from inception to January 2024. Studies that reported incidence of CVA and dementia in patients with AF were. Data from each study were combined by a random-effects model. The results were reported in risk ratios with 95% confidence intervals (CIs). Results: A total of 29 studies and 379,993 patients (mean age 58 ± 4 years, 30% women) were included in the analysis. Mean follow-up was 36 ± 23 months (range 12-120 months). Patients who underwent CA of AF had a lower risk of developing CVA compared with medical management (odds ratio [OR] 0.54, 95% CI 0.42-0 69, I Conclusion: CA of AF resulted in lower risk of CVA and dementia compared with medical management alone at long-term follow-up.

Indexed as

AblationAtrial fibrillationCVADementiaOutcomes

Identifiers

PMID40224261
PMCPMC11993796

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.