Evidence map›Paper›PMID 40225554›Full record

ArticleCureus2025

Central Nervous System Metastases in Endometrial Carcinoma: A Case Series.

Luke Ross, Kelsey Carey, Robert Koenigsberg

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luke RossRadiology, Temple University Hospital, Philadelphia, USA.
Kelsey CareyRadiology, Temple University Hospital, Philadelphia, USA.
Robert KoenigsbergNeuroradiology, Temple University Hospital, Philadelphia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central nervous system metastases from endometrial carcinoma are a rare occurrence and suggest that metastatic endometrial carcinoma can have variable presentations. In this case report, we present three separate cases of patients diagnosed with endometrial carcinoma with metastasis to the central nervous system. The first case presents a woman with grade 2 endometrioid adenocarcinoma with mucinous and clear cell features found later to have skull metastasis with extradural extension. The second case presents a patient with an endometrial yolk sac tumor who, years after her primary diagnosis, was found to have metastasis to the brain. The final case is a woman with endometrial adenocarcinoma who developed brain metastases. While rare, it is important to consider the possibility of the presence of distal bone and brain metastases in patients with endometrial carcinoma. Special attention must be given when these patients report new neurologic symptoms, and one must consider early brain imaging.

Indexed as

bone metastasisbrain metastasiscns metastasisendometrial cancerskull metastasis

Identifiers

PMID40225554
PMCPMC11987574

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.