ArticleAmerican journal of translational research2025
Diagnostic value of NLR, PLR and SIRI in peritoneal dialysis-associated peritonitis.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk prediction models for peritoneal dialysis-associated peritonitis: a systematic review and meta-analysis.International urology and nephrology · 2026Pooled it
- Development and validation of a nomogram for peritoneal dialysis-associated peritonitis.Renal failure · 2026Article
- Risk factors and microbiological characteristics of bacterial peritonitis in patients undergoing peritoneal dialysis.BMC nephrology · 2026Article
- FT3 Levels and Systemic Inflammation: Evidence From a Population-Based NHANES Analysis.Mediators of inflammation · 2026Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic value of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SIRI) in peritoneal dialysis-associated peritonitis (PDAP).
methodsIn this retrospective study, the clinical data from 130 patients who underwent peritoneal dialysis (PD) for the first time at the Cangzhou Central Hospital from January 2019 to January 2022 were rigorously reviewed and analyzed. Based on the occurrence of PDAP during treatment, patients were classified into the peritonitis group (n=31) and the non-peritonitis group (n=99). The expression levels and diagnostic value of NLR, PLR, and SIRI were analyzed in the contest of PDAP. Pearson correlation analysis was performed to examine the correlations between NLR, PLR and SIRI in PDAP patients, and the joint diagnostic value of NLR, PLR, and SIRI was evaluated. Additionally, risk factors associated with PDAP were identified.
resultsPatients in the peritonitis group were older than those in the non-peritonitis group, and experienced longer duration of dialysis (P<0.05). The peritonitis group exhibited significantly higher NLR, PLR and SIRI levels than the non-peritonitis group (P<0.001). Pearson correlation analysis revealed significant positive corrections between NLR, PLR and SIRI in PDAP patients. Logistic regression analysis identified NLR, PLR, and SIRI as independent influencing factors for the occurrence of PDAP. ROC curve analysis revealed that the combined use of NLR, PLR, and SIRI for diagnosing PDAP yielded an AUC of 0.935, significantly higher than their individual predictions, along with superior diagnostic accuracy.
conclusionNLR, PLR, and SIRI are independent risk factors for the occurrence of PDA. These indices hold significant diagnostic value for PDAP, and their combined utilization can enhance diagnostic accuracy.
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