ArticleAmerican journal of translational research2025
Age-related differences in coronary artery lesions and short-term prognosis in acute coronary syndrome patients.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Distinct clinical profiles and outcomes in young versus older adults with acute coronary syndrome: a comparative cohort study.Journal of cardiothoracic surgery · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore age-related differences in coronary artery lesions, lesion characteristics, and short-term prognosis in acute coronary syndrome (ACS) patients.
methodsA retrospective analysis was conducted on 198 ACS patients (February 2019-January 2024). Patients were grouped by age: < 40 years (low-age), 40-60 years (middle-age), and > 60 years (high-age). We compared clinical data, coronary angiography results, lesion characteristics, and short-term major adverse cardiac event (MACE) occurrence across the groups. Pearson or Spearman correlation was used to assess relationships, and ROC curves were employed to evaluate the predictive ability for MACE.
resultsThe high-age group had significantly higher Gensini scoring and Global Registry of Acute Coronary Events (GRACE) scores (both P < 0.001), more diseased branches, and a higher proportion of non-calcified plaques. MACE incidence was highest in the high-age group. Age correlated positively with hypertension, hyperlipidemia, triglycerides, Gensini score, GRACE score, and the number of diseased branches, and negatively with hemoglobin levels (all P < 0.05). Age showed the strongest predictive ability for short-term MACE (AUC: 0.673, sensitivity: 71.0%).
conclusionElderly ACS patients exhibit more severe coronary lesions and a higher incidence of MACE. Age is a significant predictor of short-term MACE and correlates with various clinical and angiographic indicators.
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