Evidence map›Paper›PMID 40226394›Full record

ArticleJournal of tissue engineering and regenerative medicine2023

Epiretinal Amniotic Membrane Influences the Cellular Behavior of Profibrotic Dedifferentiated Cells of Proliferative Vitreoretinopathy

Anna Hillenmayer, Laura D Strehle, Christina Hilterhaus, Andreas Ohlmann, Christian M Wertheimer, Armin Wolf

Abstract read
In one paragraph

Article in Journal of tissue engineering and regenerative medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna HillenmayerDepartment of Ophthalmology, University of Ulm, Prittwitzstr. 43, Ulm 89075, Germany.ORCID 0000-0001-9433-3292
Laura D StrehleDepartment of Ophthalmology, University of Ulm, Prittwitzstr. 43, Ulm 89075, Germany.ORCID 0009-0005-1433-9288
Christina HilterhausDepartment of Ophthalmology, University of Ulm, Prittwitzstr. 43, Ulm 89075, Germany.ORCID 0009-0003-7187-0812
Andreas OhlmannDepartment of Ophthalmology, Ludwig-Maximilians University, Mathildenstr. 8, Munich 80336, Germany.ORCID 0000-0002-7101-9361
Christian M WertheimerDepartment of Ophthalmology, University of Ulm, Prittwitzstr. 43, Ulm 89075, Germany.ORCID 0000-0002-7017-7560
Armin WolfDepartment of Ophthalmology, University of Ulm, Prittwitzstr. 43, Ulm 89075, Germany.ORCID 0000-0002-6991-2214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proliferative vitreoretinopathy (PVR) as a rare fibrotic ocular disease is the main reason for failure of retinal detachment surgery and a reduced prognosis following surgery. Amniotic membrane (AM) is a versatile surgical tool for tissue stabilization, antifibrotic properties, and regeneration. Initial clinical case studies now demonstrated intravitreal tolerance as well as good anatomical and functional results for degenerative retinal diseases. Due to its diverse wound healing properties, AM could have promoting, suppressive, or no effects on PVR. To illuminate the potential of epiretinal AM transplantation in complex retinal detachment cases, we investigated its influence on human primary PVR (hPVR) cells

Indexed as

AmnionCell DedifferentiationEpiretinal MembraneVitreoretinopathy, ProliferativeAgedCell AdhesionCell MovementCell ProliferationFemaleFibrosisHumansMaleMiddle Aged

Identifiers

PMID40226394
PMCPMC11918902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.