Evidence map›Paper›PMID 40226444›Full record

ArticleLife medicine2025

A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement.

Aging Biomarker Consortium, Xiaolong Fu, Si Wang, Yunhao Wu, Yu Sun, Wenwen Liu, Xin Xi, Geng-Lin Li, Ke Liu, Wei Yuan and 32 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

Aging Biomarker Consortium
Xiaolong FuShandong Provincial Hospital, Medical Science and Technology Innovation Center, School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China.
Si WangAdvanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
Yunhao WuShandong Provincial Hospital, Medical Science and Technology Innovation Center, School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China.
Yu SunDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.
Wenwen LiuDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan 250022, China.
Xin XiDepartment of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Beijing 100000, China.
Geng-Lin LiENT Institute and Department of Otorhinolaryngology, Eye and ENT Hospital, Fudan University, Shanghai 200433, China.
Ke LiuDepartment of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital of Capital Medical University, Beijing 100050, China.
Wei YuanDepartment of Otolaryngology & Head and Neck, Chongqing General Hospital, Chongqing 401147, China.
Fangyi ChenDepartment of Biology, South University of Science and Technology of China, Shenzhen 518000, China.
Hongyang WangSenior Department of Otolaryngology Head and Neck Surgery, the sixth Medical Center of Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing 100853, China.
Tao YangDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200023, China.
Yuhe LiuDepartment of Otolaryngology, Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Jialin ZhengCollaborative Innovation Center for Brain Science, Tongji University, Shanghai 200092, China.
Haibo ShiDepartment of Otolaryngology Head & Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Jing QuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Institute for Stem Cell and Regenerative Medicine, University of Chinese Academy of Sciences, Beijing 100101, China.ORCID https://orcid.org/0000-0002-3988-5067
Xiaowei ChenDepartment of Otolaryngology, Peking Union Medical College Hospital, Beijing 100730, China.
Limin SuoDepartment of Otolaryngology, Head and Neck Surgery, the Second Hospital of Shanxi Medical University, Taiyuan 030001, China.
Yideng HuangDepartment of Otolaryngology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Xinbo XuDepartment of Otolaryngology, Qilu Hospital of Shandong University, Jinan 250012, China.
Xuxia TangOtolaryngology Department, Zhejiang Provincial Hospital of TCM, Hangzhou 310003, China.
Xiaojun LiFrontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Lei XuDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan 250022, China.
Xia GaoDepartment of Otolaryngology-Head and Neck Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline (Laboratory), Nanjing 210008, China.
Lisheng YuDepartment of Otolaryngology, Head and Neck Surgery, People's Hospital, Peking University, Beijing 100044, China.
Yilai ShuENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, MOE Engineering Research Center of Gene Technology, Fudan University, Shanghai 200031, China.
Weiqi ZhangChina National Center for Bioinformation, Beijing 100101, China.ORCID https://orcid.org/0000-0002-8885-5104
Jinpeng SunNHC Key Laboratory of Otorhinolaryngology, Qilu hospital and School of Basic Medical Sciences, Shandong University, Jinan 250012, China.
Huijun YuanDepartment of Oto-Rhino-Laryngology, West China Hospital, Sichuan University, Chengdu 610000, China.
Shusheng GongDepartment of Otolaryngology-Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Wenyan LiENT institute and Otorhinolaryngology Department of Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200031, China.
Xiulan MaDepartment of Otolaryngology Head and Neck Surgery, Shengjing Hospital of China Medical University, Shenyang 110000, China.
Dingjun ZhaDepartment of Otolaryngology Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710000, China.
Jiangang GaoSchool of Life Science and Key Laboratory of the Ministry of Education for Experimental Teratology, Shandong University, Jinan 250100, China.
Huawei LiENT institute and Otorhinolaryngology Department of Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200031, China.
Zuhong HeDepartment of Otorhinolaryngology‑Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Guang-Hui LiuState Key Laboratory of Membrane Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China.ORCID https://orcid.org/0000-0001-9289-8177
Gang PeiCollaborative Innovation Center for Brain Science, School of Life Science and Technology, Tongji University, Shanghai 200092, China.
Weijia KongDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Haibo WangDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan 250022, China.
Renjie ChaiState Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 210096, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hearing is one of the most vital sensory functions in human beings and a crucial means of perceiving and acquiring information from the natural environment. The advancement of human society is closely linked to the development of language, with hearing serving as the foundation for verbal communication. As individuals age, the deterioration of the auditory system becomes a significant factor contributing to sensory impairments in the elderly. In addition to hearing loss, the aging of the auditory system is also associated with cognitive decline and psychosocial disorders, which severely impact the quality of life for older adults. Currently, there are no effective treatments or interventions available for addressing the aging of the auditory system. Therefore, identifying biomarkers of the auditory system aging is of great significance. The Aging Biomarker Consortium of China has conducted a comprehensive evaluation of aging biomarkers in the auditory system, focusing on three dimensions: morphological, functional, and humoral biomarkers. This initiative aims to establish a foundation for assessing the degree of aging in the auditory system and to promote the management of auditory health in an aging society, ultimately enhancing the auditory health of the elderly population both in China and globally.

Identifiers

PMID40226444
PMCPMC11992615

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.